The Association Between Tea Consumption Timing and Kidney Function: Insights From a National Survey.

Tea consumption has garnered significant attention due to its rich polyphenolic compounds and associated health benefits. However, existing research primarily focuses on the quantity of tea intake, while studies examining tea consumption timing remain limited. Given the circadian rhythm of kidney function and its metabolic implications, this study investigated the association between tea consumption timing, estimated glomerular filtration rate (eGFR), and chronic kidney disease (CKD) risk. Based on NHANES data from 2005 to 2018, 40,496 participants were included. Participants were grouped into high, medium, low, and non-tea intake groups. Additionally, tea consumption timing was categorized into four periods: dawn to noon, noon to afternoon, afternoon to night, and night to dawn. Multivariate regression models and restricted cubic spline models were employed to evaluate the associations between tea consumption timing, intake levels, and eGFR. Tea consumption timing showed a significant time-dependent association with eGFR levels. After adjusting for confounders, dawn-to-noon tea consumption demonstrated the strongest positive association with higher eGFR (3.18 mL/min/1.73 m