Evidence mapPaperPMID 41019191Full record

ReviewClinical Medicine Insights. Cardiology2025

Two Sides of Triglycerides in Atherogenesis: An Essential Contributor.

Anastasia V Poznyak, Sergey Kozlov, Gulalek A Babayeva, Vasily N Sukhorukov, Alexander N Orekhov

Abstract readReview
In one paragraph

Review in Clinical Medicine Insights. Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anastasia V PoznyakInstitute for Atherosclerosis Research, Moscow, Russia.ORCID https://orcid.org/0000-0002-1516-1320
Sergey KozlovChazov National Medical Research Center of Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia.
Gulalek A BabayevaInstitute of Experimental Cardiology, National Medical Research Center of Cardiology, Moscow, Russia.
Vasily N SukhorukovInstitute of General Pathology and Pathophysiology, Laboratory of Angiopathology, Moscow, Russia.
Alexander N OrekhovInstitute of General Pathology and Pathophysiology, Laboratory of Angiopathology, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is chronic arterial wall damage, which often results in cardiovascular disease development. Since atherosclerosis is almost asymptomatic, it is difficult to detect this condition, but it is even more difficult to deal with the consequences. The reasons for the development of atherosclerosis are still not completely clear, but the mechanisms involved in atherogenesis are known. Among them, lipid metabolism alterations, oxidative stress, as well as impaired mitochondrial function take pride of place. In our review, we want to dwell in more detail on such a component as lipid metabolism disorders. In particular, triglycerides, their levels, and influence on the development of the disease. Triglycerides provide the second-largest source of energy. In the context of atherosclerosis, the question arises, is an increase in the level of triglycerides in the blood a cause, a biomarker, or a consequence of the processes accompanying atherogenesis?

Indexed as

Atherosclerosislipidstriglycerides

Identifiers

PMID41019191
PMCPMC12461037

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.