Evidence map›Paper›PMID 41019340›Full record

ArticleFrontiers in endocrinology2025

Impact of genotyping (

Shimaa Abdelsattar, Hiba S Al-Amodi, Hala F M Kamel, Zeinab A Kasemy, Ehab Darwish, Asmaa Mosbeh, Ayman A Sakr, Hanaa M Elgazzar, Mervat Abdelkareem, Mai Abozeid and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shimaa AbdelsattarClinical Biochemistry and Molecular Diagnostics Department, National Liver Institute, Menoufia University, Shebin El-Kom, Egypt.
Hiba S Al-AmodiBiochemistry Department, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Hala F M KamelBiochemistry Department, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Zeinab A KasemyPublic Health and Community Medicine Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
Ehab DarwishDepartment of Hepatology, Gastroentrology and Infectious Diseases, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Asmaa MosbehDepartment of Pathology, National Liver Institute, Menoufia University, Shebin El-Kom, Egypt.
Ayman A SakrTropical Medicine Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
Hanaa M ElgazzarMedical Microbiology and Immunology, National Liver Institute, Menoufia University, Shebin El-Kom, Egypt.
Mervat AbdelkareemHepatology and Gastroenterology Department, National Liver institute, Menoufia University, Shebin El-Kom, Egypt.
Mai AbozeidHepatology and Gastroenterology Department, National Liver institute, Menoufia University, Shebin El-Kom, Egypt.
Shimaa K ZewainInternal Medicine Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt, Shebin El-Kom, Egypt.
Hanan M BedairClinical Pathology Department, National Liver Institute, Menoufia University, Shebin El-Kom, Egypt.
Sabry M AbdelmageedClinical Biochemistry and Molecular Diagnostics Department, National Liver Institute, Menoufia University, Shebin El-Kom, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Numerous risk loci have been identified to have an essential role in Metabolic associated steatotic liver disease (MASLD) susceptibility and progression. The role of membrane-bound O-acyltransferase domain containing 7 ( Methods: We enrolled 142 patients with varying degrees of MASLD and 142 healthy controls with no evidence of MASLD. All subjects underwent biochemical tests and genotyping of Results and discussion: The study revealed that T allele and T/T genotype of

Indexed as

AcyltransferasesFatty LiverGenotyping TechniquesLiver CirrhosisMembrane ProteinsMetabolic DiseasesProtein Tyrosine Phosphatase, Non-Receptor Type 2AdultCase-Control StudiesDisease ProgressionEgyptFemaleGenetic Predisposition to DiseaseGenetic Risk ScoreGenotypeHumansAcyltransferasesMBOAT7 protein, humanMembrane ProteinsProtein Tyrosine Phosphatase, Non-Receptor Type 2PTPN2 protein, humanfibrosisgenotypingMASLDMBOAT7PTPN2rs2542151rs641738

Identifiers

PMID41019340
PMCPMC12460093

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.