Evidence map›Paper›PMID 41019372›Full record

ArticleiScience2025

Comparative effects of hemodialysis modalities on microparticle induction and neutrophil activation in a randomized cross-over study.

Awirut Charoensappakit, Jirarat Eiamcharoenying, Kritsanawan Sae-Khow, Suwasin Udomkarnjananun, Khajohn Tiranathanagul, Asada Leelahavanichkul

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Awirut CharoensappakitCenter of Excellence on Translational Research in Inflammation and Immunology (CETRII), Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Jirarat EiamcharoenyingDivision of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Kritsanawan Sae-KhowCenter of Excellence on Translational Research in Inflammation and Immunology (CETRII), Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Suwasin UdomkarnjananunDivision of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Khajohn TiranathanagulDivision of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Asada LeelahavanichkulCenter of Excellence on Translational Research in Inflammation and Immunology (CETRII), Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the clearance of uremic toxins is comparable between expanded hemodialysis using a medium cut-off dialyzer (MCO+HDX) and online hemodiafiltration (OL-HDF), their effects on pro-inflammatory mediators have not been clarified. This study conducted a randomized cross-over study involving 12 thrice-weekly patients with hemodialysis who sequentially received MCO+HDX and OL-HDF with a washout period. Microparticles (MPs) and neutrophil activation were evaluated pre- and post-dialysis. OL-HDF showed elevated post-dialysis annexin V-positive MPs, predominantly from platelets and neutrophils.

Indexed as

Cell biologyImmunology

Identifiers

PMID41019372
PMCPMC12466253

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.