ReviewMaterials today. Bio2025
Functional scaffolds design strategies for retinal repair and regeneration.
Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Multimodal imaging for early drusen detection: RM-SLO as a promising imaging approach.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The growing strain placed on both society and the healthcare system due to an ageing population should not be underestimated. Age-related macular degeneration (AMD) is a leading cause of blindness worldwide and is projected to affect 288 million people globally by 2040. Current treatment options for AMD primarily focus on disease management rather than offering a definitive cure. Retinal tissue engineering, which aims to develop targeted regenerative strategies to restore or replace damaged retinal tissues, offers pioneering advances that could provide curative solutions for AMD and revolutionize its therapeutic landscape. This review aims to provide a comprehensive overview of biomaterial strategies for retinal repair and regeneration, with a particular focus on scaffold design. To effectively address the underlying causes of retinal degenerative diseases and develop functional scaffolds, the review examines the retinal anatomy, the vision-impairing diseases associated with degeneration and relevant cell types. Building on this foundation, it further discusses various scaffold design strategies, including the selection of biomaterials, the structural and mechanical mimicry of native tissues, and the fabrication of scaffolds for co-culturing. Beyond current strategies, we also explore potential features, such as electrically conductive and photo-responsiveness, that could shape the future of scaffold design in retina tissue engineering. Collectively, these insights provide a robust framework to drive and accelerate the next generation of scaffold development for retinal tissue engineering.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.