Evidence mapPaperPMID 41019557Full record

ArticleFrontiers in nutrition2025

Regular extra-virgin olive oil intake independently associates with lower abdominal obesity.

Carlo De Matteis, Lucilla Crudele, Ersilia Di Buduo, Salvatore Cantatore, Fabio Novielli, Silvia Cultrera, Angela Fulvia Tricase, Maria Arconzo, Marilina Florio, Raffaella Maria Gadaleta and 3 more

Abstract read
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Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Carlo De Matteis *Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Lucilla Crudele *Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Ersilia Di BuduoDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Salvatore CantatoreDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Fabio NovielliDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Silvia CultreraDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Angela Fulvia TricaseDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Maria ArconzoDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Marilina FlorioDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Raffaella Maria GadaletaDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Elena PiccininDepartment of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari "Aldo Moro", Bari, Italy.
Marica CarielloDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Antonio MoschettaDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Abdominal obesity is a major global health burden, driving risk for cardiovascular disease, type 2 diabetes, and cancer. The Mediterranean Diet (MedDiet), recognized for its cardiometabolic benefits, emphasizes Extra-Virgin Olive Oil (EVOO) as a primary fat source. We previously validated the Chrono Med Diet Score (CMDS), an index integrating dietary quality and chrono-nutritional principles, and demonstrated its associations with abdominal adiposity and cancer incidence. Although EVOO is central to the MedDiet, mechanisms related to its specific contributions to metabolic health remain partial. In the present study, we investigated the relationship between consistent EVOO intake frequency, MedDiet adherence (CMDS), and anthropometric outcomes. Methods: We analyzed data from 16,273 adults (46.5% male) who completed the CMDS-based online survey since April 2023. Data included age, sex, height, weight, waist circumference (WC), Body Mass Index (BMI) and dietary/lifestyle information. EVOO intake frequency was categorized as: sporadic (<3 days/week), frequent (≥3 but <6 days/week), or regular (≥6 days/week), based on ~25 g/day (~2 tablespoons). Statistical analyses included Student's t-tests, ANOVA with Bonferroni correction, mediation analysis, and multivariable logistic regression adjusting for confounders. Results: Significant sex differences were observed in age, BMI, WC, and CMDS. Participants with regular EVOO intake were significantly older (55.9 ± 8.1 years) than sporadic (53.9 ± 7.1) and frequent (54.1 ± 7.7) consumers ( Conclusion: In this large cohort, regular EVOO consumption, while defining higher CMDS adherence, is independently associated with lower BMI and WC. EVOO exerts a dual role in metabolic health, both mediating and independently enhancing the relationship between chrono-Mediterranean diet adherence and reduced abdominal obesity. Non-regular EVOO intake emerges as a strong risk factor for visceral adiposity, irrespective of overall diet quality.

Indexed as

abdominal obesityextra-virgin olive oilMediterranean dietnutritionwaist circumference

Identifiers

PMID41019557
PMCPMC12461093

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.