Evidence mapPaperPMID 41019996Full record

ArticleFrontiers in pharmacology2025

Dehydrozaluzanin C inhibits colon cancer cell proliferation, apoptosis and cycle arrest through peroxisome proliferator-activated receptor γ (PPARγ) activation.

Shan-Shan Li, Zhao-Ting Li, Xiao-Qing Zhu, Xu Li, Xi-Ke Xu, Xian-Peng Zu, Xian Li, Yun-Heng Shen

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shan-Shan Li *Center of Clinical Pharmacy, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Zhao-Ting Li *Department of Phytochemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Xiao-Qing ZhuDepartment of Phytochemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Xu LiDepartment of Phytochemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Xi-Ke XuDepartment of Phytochemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Xian-Peng ZuDepartment of Phytochemistry, School of Pharmacy, Naval Medical University, Shanghai, China.
Xian LiSchool of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, Yunnan, China.
Yun-Heng ShenDepartment of Phytochemistry, School of Pharmacy, Naval Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dehydrozaluzanin C (DC) is a sesquiterpene lactone isolated from Asteraceae plant

Indexed as

apoptosis inductioncolon cancercycle arrestDehydrozaluzanin CPPARγ activation

Identifiers

PMID41019996
PMCPMC12461092

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.