Evidence map›Paper›PMID 41020537›Full record

Observational studyOrthodontics & craniofacial research2025

Nocturnal Autonomic Nervous System and Jaw Muscle Activities and Ramus Height in Children.

Myriam Hamieh, Laura R Iwasaki, Elizabeth Palmer, Dongseok Choi, Jeffrey C Nickel, Hongzeng Liu

Abstract readObservational Study
In one paragraph

Observational study in Orthodontics & craniofacial research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Myriam HamiehPrivate Practice, Clackamas, Oregon, USA.
Laura R IwasakiDepartment of Oral and Craniofacial Sciences, Oregon Health & Science University, Portland, Oregon, USA.
Elizabeth PalmerDivision of Pediatric Dentistry, Department of Regenerative and Reconstructive Sciences, Oregon Health & Science University, Portland, Oregon, USA.
Dongseok ChoiOregon Health & Science University-Portland State University, School of Public Health, Portland, Oregon, USA.
Jeffrey C NickelDivision of Orthodontics, Department of Oral and Craniofacial Sciences, Oregon Health & Science University, Portland, Oregon, USA.ORCID https://orcid.org/0000-0001-5239-082X
Hongzeng LiuDepartment of Oral and Craniofacial Sciences, Oregon Health & Science University, Portland, Oregon, USA.

Funding

Mechanobehavior distinguishes mandibular growth differences in two facial typesR01DE028548 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI IWASAKI, LAURA R · 2019 to 2023
$2.9M
American Association of Orthodontists FoundationNational Institute for Dental and Craniofacial Research R01DE028548NIDCR NIH HHS R01 DE028548
6 · The paper itself

Abstract

objectiveMandibular growth is influenced by function. This study tested for correlation amongst nocturnal autonomic nervous system (ANS) and jaw muscle activities and mandibular ramus height. MATERIALS AND

methodsAccording to Institutional Review Board oversight, children with skeletal Class II malocclusions were enrolled in this observational study. Subjects had cone-beam computed tomography images, participated in protocols to quantify jaw muscle activity per bite-force, and were trained to use portable recorders to collect jaw muscle and heart rate variability (HRV) data over four nights at home. Night-time ultradian cycling of ANS activity was characterised by fitting a polynomial to the HRV measures of sympathovagal tone (low/high frequency spectral powers, LF/HF). Twenty-minute windows around each inflection point of this polynomial were identified, within which HRV measures and jaw muscle activities (Duty Factor, DF) were quantified. DF versus HRV measures (DF/HRV) were plotted for each subject, and regression slopes calculated. Non-linear regression analysis was used to test for correlation between DF/HRV slopes, age (years), and ramus height (mm).

resultsThirteen (eight males, five females) of 15 children enrolled completed protocols. DF versus LF/HF had average R

conclusionsMandibular ramus height may reflect the influence of sympathovagal tone on nocturnal jaw muscle activity in children.

Indexed as

Autonomic Nervous SystemCircadian RhythmMandibleMasticatory MusclesBite ForceChildCone-Beam Computed TomographyFemaleHeart RateHumansMaleMalocclusion, Angle Class IIMasseter Muscleautonomic nervous systemfacial typegrowth modificationheart rate variabilitymasticatory muscle activityramus height

Identifiers

PMID41020537
PMCPMC13102502

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.