ArticleIndian journal of pediatrics2025
Impact of Wasting on the Severity of Rotavirus and Non-rotavirus Diarrhea in Children Aged Under 5 Years Hospitalized with Acute Gastroenteritis in Kerala, India.
Article in Indian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis analysis assessed the relationship between wasting and severity of rotavirus and non-rotavirus diarrhea among children hospitalized with acute gastroenteritis in Kerala.
methodsChildren aged under 5 y admitted to sentinel hospitals in North, Central, and South Kerala with acute gastroenteritis between November 2020 and December 2023 were prospectively enrolled. Sociodemographic, anthropometric, and clinical data were collected using a case report form, and stool samples were tested for rotavirus using an enzyme-linked immunosorbent assay. Anthropometry was performed according to World Health Organization guidelines.
resultsOf the 1,142 children aged under 5 y admitted to the sentinel hospitals with acute gastroenteritis during the study period, 666 were enrolled in the study. Of the 643 children with stool samples tested for rotavirus, 115 (17.7%) were positive for rotavirus. Compared with children with wasting, children without wasting were (significantly more likely to have received ≥ 1 dose of rotavirus vaccine (69.5% vs. 60.2%; p = 0.022). In a subgroup analysis of children with wasting, compared with rotavirus-negative children, rotavirus-positive children were significantly more likely to develop severe to very severe disease (odds ratio: 5.31, 95% confidence interval: 2.28-12.34; p = 0.001).
conclusionsIn children with wasting, rotavirus diarrhea was more severe than non-rotavirus diarrhea. Strategies to prevent and treat diarrhea should target children with wasting, who are at greater risk of severe disease. Maintaining high rotavirus vaccination coverage and measures to reduce the incidence of wasting are necessary to reduce incidence of severe diarrhea.
Indexed as
Identifiers
41021176What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.