Observational studyNeuropsychology2026
Pathway analysis of cognitive resilience factors and cognitive function in the Long Life Family Study (LLFS).
Observational study in Neuropsychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
Abstract
objectiveFamilial longevity, educational attainment, and engagement in cognitively stimulating activities are independently protective for cognitive aging, yet little is known about how these factors relate with one another. We explored the interplay between familial longevity, life exposures that confer cognitive resilience, and cognitive function in the Long Life Family Study.
methodA series of Bayesian hierarchical regression models was used to examine the associations among familial longevity, educational attainment, participation in cognitively stimulating activities, and neuropsychological test performance in several cognitive domains in an ancillary observational study of Long Life Family Study family members and a referent cohort (
resultsReferents had greater engagement in cognitive activities, and in turn, those with higher levels of education and cognitive activity exhibited better neuropsychological performance. Greater cognitive activity was specifically associated with better executive functioning, episodic memory, and language scores. Although Long Life Family Study family members engaged in cognitive activities less often than referents, they performed better on tests of episodic memory, and matched performance on tests of executive function, language, and visuoconstruction.
conclusionsThese results suggest that familial longevity and engagement in cognitively stimulating activities represent two distinct pathways that contribute to preserved cognition in older adulthood, though these findings should be replicated in more diverse samples. Furthermore, these unique pathways differ across tests and cognitive domains. (PsycInfo Database Record (c) 2026 APA, all rights reserved).
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