Evidence map›Paper›PMID 41021879›Full record

ReviewJCO global oncology2025

Adoption and Implementation of Affordable Cancer Technologies in El Salvador: Identifying Implementation Strategies for Successful Cervical Cancer Prevention in Resource-Limited Settings.

Montserrat Soler, Karla Alfaro, Juan Carlos Rauda, Elizabeth Torres, José Roberto Pérez, Freddy Méndez, Gabriel Conzuelo Rodriguez, Marina A Chacon, Mayra Patricia Erazo, Rachel Masch and 2 more

Abstract readReview
In one paragraph

Review in JCO global oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Montserrat SolerObstetrics and Gynecology Institute, Cleveland Clinic, Cleveland, OH.ORCID 0000-0002-1193-8710
Karla AlfaroBasic Health International, Pittsburgh, PA.
Juan Carlos RaudaBasic Health International, Pittsburgh, PA.
Elizabeth TorresBasic Health International, Pittsburgh, PA.
José Roberto PérezBasic Health International, Pittsburgh, PA.
Freddy MéndezBasic Health International, Pittsburgh, PA.
Gabriel Conzuelo RodriguezBasic Health International, Pittsburgh, PA.
Marina A ChaconEl Salvador Ministry of Health, San Salvador, El Salvador.
Mayra Patricia ErazoEl Salvador Ministry of Health, San Salvador, El Salvador.
Rachel MaschBasic Health International, Pittsburgh, PA.ORCID 0000-0002-3761-858X
Eveline MumenthalerBasic Health International, Pittsburgh, PA.
Miriam CremerObstetrics and Gynecology Institute, Cleveland Clinic, Cleveland, OH.ORCID 0000-0003-2006-2439

Funding

TeleMed: Comparison of cervical intraepithelial neoplasia 2/3 treatment outcomes with a portable LMIC-adapted thermal ablation device vs. gas-based cryotherapyR01CA218195 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI CREMER, MIRIAM · 2018 to 2023
$3.7M
CryoPen: An Innovative Treatment for Cervical Precancer in Low-Resource SettingUH3CA189883 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI CREMER, MIRIAM · 2016 to 2018
$2.8M
CryoPen: An Innovative Treatment for Cervical Precancer in Low-Resource SettingUH2CA189883 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI CREMER, MIRIAM · 2014 to 2015
$985k
NCI NIH HHS R01 CA218195NCI NIH HHS UH2 CA189883NCI NIH HHS UH3 CA189883
6 · The paper itself

Abstract

As part of the affordable cancer technology program, our team developed and tested a portable thermal ablation (TA) cervical precancer treatment. This research helped support subsequent implementation of the technology in El Salvador. Here, we review successful implementation strategies deployed during the process and point to challenges and implications for other low- and middle-income countries (LMICs). We use the exploration, preparation, implementation, and sustainment framework to guide the discussion and identify associated implementation strategies used during each phase. Significant strategies were the development and maintenance of multi-actor partnerships and accessing new funding to introduce innovations to the country. In this case, planning for implementation began before the decision to adopt TA. The case of El Salvador highlights the need for such pragmatic approaches to shorten the time between scientific research and clinical practice in LMICs. The impact of these efforts has been significant: El Salvador has gone from one of the countries with the lowest cervical cancer screening rates in the region to one that can potentially meet elimination targets in the coming decades. This experience can serve as a blueprint for cervical cancer control efforts in other LMICs.

Indexed as

Uterine Cervical NeoplasmsDeveloping CountriesEarly Detection of CancerEl SalvadorFemaleHumansResource-Limited Settings

Identifiers

PMID41021879
PMCPMC12483179

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.