ArticleWorld journal of gastrointestinal surgery2025
Effect of comorbid gastroesophageal reflux disease on laryngopharyngeal reflux disease: Clinical characteristics and risk factors.
Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundResearch thoroughly examining how gastroesophageal reflux disease (GERD) affects clinical presentations in patients with laryngopharyngeal reflux disease (LPRD) and exploring the associated triggers is limited.
aimTo investigate the effect of comorbid GERD on the clinical characteristics of patients with LPRD and determine risk contributors.
methodsIn total, 150 patients with LPRD admitted between October 2022 and October 2024 were divided into the GERD (
resultsCompared with the non-GERD group, the GERD group, with a notably higher BMI, included greater proportions of older patients, female patients, smokers, and alcohol users and a higher prevalence of bothersome cough, heartburn, chest pain, and stomach pain; however, excessive phlegm or postnasal drip was less common. Additionally, patients with LPRD and comorbid GERD had notably higher RSI and RFS scores. Age (
conclusionComorbid GERD exacerbates clinical manifestations of patients with LPRD. Advanced age, female sex, smoking, and alcohol consumption predispose patients with LPRD to GERD development.
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