Evidence map›Paper›PMID 41026827›Full record

ArticleScience signaling2025

Molecular determinants for the endocytosis of the voltage-gated K

Irene Estadella, María Navarro-Pérez, Magalí Colomer-Molera, Michael L Dustin, Alexander Sorkin, Jesusa Capera, Antonio Felipe

Abstract read
In one paragraph

Article in Science signaling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Irene EstadellaMolecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0001-5103-206X
María Navarro-PérezMolecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0001-8106-9787
Magalí Colomer-MoleraMolecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0002-2038-5265
Michael L DustinKennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.ORCID 0000-0003-4983-6389
Alexander SorkinDepartment of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.ORCID 0000-0002-4446-1920
Jesusa CaperaMolecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0002-8123-7725
Antonio FelipeMolecular Physiology Laboratory, Departament de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Avda. Diagonal 643, 08028 Barcelona, Spain.ORCID 0000-0002-7294-6431

Funding

R35 - ADMIN SUPPLEMENT - EGF Receptor Endocytosis: Mechanisms and Role in SignalingR35GM148363 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALEXANDER D SORKIN · 2023 to 2026
$1.8M
NIGMS NIH HHS R35 GM148363
6 · The paper itself

Abstract

The voltage-gated potassium channel Kv1.3 contributes to action potential conduction in sensory neurons and to sustained increases in cytoplasmic Ca

Indexed as

EndocytosisKv1.3 Potassium ChannelAnimalsHEK293 CellsHumansImmunological SynapsesLysosomesT-LymphocytesUbiquitinationKCNA3 protein, humanKv1.3 Potassium Channel

Identifiers

PMID41026827
PMCPMC12951420

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.