Evidence map›Paper›PMID 41026830›Full record

ArticleAmerican journal of physiology. Cell physiology2025

Ca

Rolando Carrisoza-Gaytán, Abigail Daily, Kayla J Wolf, Samia Lasaad, Anna Cantalupo, Pooja Nair, Ronald C van Gaal, Per Uhlén, Jennifer A Lewis, Lisa M Satlin

Abstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rolando Carrisoza-GaytánDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, United States.ORCID 0000-0001-8771-9269
Abigail DailyDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, United States.ORCID 0009-0005-0757-9873
Kayla J WolfNancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York, United States.ORCID 0000-0001-6990-0283
Samia LasaadDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, United States.ORCID 0009-0009-1101-2641
Anna CantalupoDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, United States.ORCID 0000-0002-5818-0900
Pooja NairPaulson School of Engineering and Applied Sciences and Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, United States.ORCID 0009-0006-7077-1734
Ronald C van GaalPaulson School of Engineering and Applied Sciences and Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, United States.ORCID 0000-0002-4640-4612
Per UhlénDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-1446-1062
Jennifer A LewisPaulson School of Engineering and Applied Sciences and Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts, United States.ORCID 0000-0002-0280-2774
Lisa M SatlinDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, United States.ORCID 0000-0002-1744-1748

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARATTINO, MARCELO DANIEL · 2008 to 2022
$13.4M
Resource Development CoreU54DK137329 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Gerard L Apodaca · 2023 to 2026
$4.8M
Prediction of Major Adverse Kidney Events and Recovery (Pred-MAKER) in COVID-19 PatientsR01DK118222 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Evren U. AZELOGLU · 2018 to 2026
$4.3M
Ex Vivo Generation of Functional Kidney Tissues for TransplantationUC2DK126023 · NIDDK · HARVARD UNIVERSITY · PI LEWIS, JENNIFER A. · 2020 to 2024
$4.0M
Role of piezo channels in intercalated cellsR01DK129285 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R, SATLIN, LISA M. · 2022 to 2025
$2.3M
Engineering scalable collecting duct networks for functional kidney tissueF32DK131821 · NIDDK · HARVARD UNIVERSITY · PI WOLF, KAYLA · 2022 to 2024
$181k
Dutch Research Council Rubicon grant 019.201EN.005HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) F32DK131821HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) P30DK079307HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK118222HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK129285HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) UC2DK126023NIDDK NIH HHS F32 DK131821NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK118222NIDDK NIH HHS R01 DK129285NIDDK NIH HHS U54 DK137329NIDDK NIH HHS UC2 DK126023Swedish Brain Foundation FO2024-0057-TK-138Swedish Research Council 2021-03108
6 · The paper itself

Abstract

Mechanical signals sensed by human stem cells are transduced via discrete signaling pathways to modulate developmental phenotype and function. Proximal tubules isolated from nephron lineage-derived kidney organoids undergo a developmental increase in abundance and/or activity of the basolateral mechanosensor PIEZO1 and Ca

Indexed as

Calcium SignalingInduced Pluripotent Stem CellsKidney Tubules, CollectingOrganoidsUreterCalciumCell DifferentiationCells, CulturedHumansIon ChannelsKidneyMechanotransduction, CellularCalciumIon ChannelsPIEZO1 protein, humanCa2+ dynamicskidney tubulesmechanotransductionoscillationsPIEZO1

Identifiers

PMID41026830
PMCPMC12643228

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.