Evidence map›Paper›PMID 41027852›Full record

ArticleNature communications2025

Mechanism for the substrate recognition by a eukaryotic DNA N

Qi Xu, Ying Xie, Zhubing Shi

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A PIWI protein-dependent DNA N6-adenine methylation pathway inbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qi XuSchool of Life Sciences, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-9480-4776
Ying XieZhejiang Key Laboratory of Structural Biology, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
Zhubing ShiZhejiang Key Laboratory of Structural Biology, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China. shizhubing@westlake.edu.cn.ORCID http://orcid.org/0000-0002-9624-4960

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32271264Science and Technology Department of Zhejiang Province 2023R5245Science and Technology Department of Zhejiang Province 2024SSYS0033
6 · The paper itself

Abstract

In eukaryotes, DNA N

Indexed as

DNASite-Specific DNA-Methyltransferase (Adenine-Specific)AdenineCatalytic DomainCryoelectron MicroscopyDNA MethylationModels, MolecularProtein BindingSubstrate SpecificityAdenineDNASite-Specific DNA-Methyltransferase (Adenine-Specific)

Identifiers

PMID41027852
PMCPMC12485025

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.