SynthesisFrontiers in endocrinology2025
Effects of exercise on bone metabolism in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Exercise-Induced Regulation of Bone Remodeling via Mitophagy: A Review of Current Evidence.Biomolecules · 2026Review
- Molecular Mechanisms and Therapeutic Potential of Puerariae Lobatae Radix in Bone Metabolism: A Comprehensive Review.Drug design, development and therapy · 2026Review
- Exercise-induced osteoimmune crosstalk: a virtuous cycle between bone remodeling and immune regulation.Frontiers in endocrinology · 2026Review
- Tai Chi Exercise and Bone Health in Women at Perimenopausal and Postmenopausal Stages: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To assess the impact of exercise on bone metabolism in postmenopausal women through meta-analysis, and to offer evidence-based guidance for preventing and managing osteoporosis in this population. Methods: We searched PubMed, Embase, and other databases using keywords such as "exercise," "postmenopausal women," and "bone metabolism" to identify randomized controlled trials published up to 2024 on the effect of exercise on bone metabolism in postmenopausal women. Studies were selected according to predefined inclusion and exclusion criteria. Data were analyzed using Review Manager 5.4 and Stata17. Study quality was assessed with the Cochrane risk-of-bias tool. Effect sizes were pooled as standardized mean differences( Results: A meta-analysis of 24 studies(1067 subjects total)showed that exercise significantly elevated the levels of alkaline phosphatase(ALP)( Conclusion: Exercise significantly improves bone metabolism in postmenopausal women by reducing bone resorption and promoting bone formation. Aerobic exercise lowers CTX levels, while both aerobic and resistance exercise increase OC levels. Short-term (≤6 months) and moderate-length (≤60 minutes/session) interventions are particularly effective. However, more high-quality randomized controlled trials are needed to confirm these benefits. Systematic review registration: https://www.crd.york.ac.uk/, identifier CRD42024610810.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.