Evidence map›Paper›PMID 41031315›Full record

ArticleFrontiers in robotics and AI2025

Gödelian embodied self-referential genomic intelligence: lessons for AI and AGI from the genomic blockchain.

Sheri Markose

Abstract read
In one paragraph

Article in Frontiers in robotics and AI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sheri MarkoseDepartment of Economics, University of Essex, Colchester, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The security of code-based digital records is a major concern of the 21st century. AI and artificial general intelligence (AGI) can be hacked to pieces by digital adversaries, and some AI objectives can lead to existential threats. The former arises from sitting duck problems that all software systems are vulnerable to, and the latter include control and misalignment problems. Blockchain technology, circa 2009, can address these problems: hashing algorithms rely on a consensus mechanism in manmade software systems to keep early blocks of software immutable and tamper-proof from digital malware, while new blocks can be added only if consistently aligned with original blocks. There is evidence that the ancient precedent of the genomic blockchain, underpinning the unbroken chain of life, uses a self-referential rather than a consensus-based hashing algorithm. Knowledge of self-codes permits biotic elements to achieve a hack-free agenda by self-reporting that they have been "negated," or hacked, exactly implementing the Gödel sentence from foundational mathematics of Gödel, Turing, and Post (G-T-P). This results in an arms race in open-ended novelty to secure the primacy of original self-codes. Selfhood and autonomy are staples of neuroscience on complex self-other social cognition and increasingly of autonomous AGI agents capable of end-to-end programmed self-assembly. My perspective is that self-referential G-T-P information processing, first found in the adaptive immune system of jawed fish 500 mya and more recently in mirror neuron systems of humans, has enabled code-based self-organized intelligent systems like life to survive over 3.7 billion years. Some lessons for AGI can be gleaned from this discussion.

Indexed as

blockchaincontrol or misalignment problemgenomic intelligenceGödel sentenceself-reference

Identifiers

PMID41031315
PMCPMC12477408

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.