ArticleAnnals of medicine2025
Preoperative electroacupuncture for prevention of postoperative delirium in older adults undergoing total knee arthroplasty: protocol for a multicenter randomized controlled trial.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
introductionPostoperative delirium is a common and serious complication following total knee arthroplasty in older adults, leading to increased mortality, prolonged hospitalization, and cognitive decline. Although electroacupuncture has shown promise in improving cognitive function, its efficacy in preventing postoperative delirium following arthroplasty remains unknown. This study investigates whether preoperative electroacupuncture prevents postoperative delirium in older adults undergoing total knee arthroplasty. METHODS AND ANALYSIS: This multicenter, randomized, double-blind, sham-controlled trial will enroll 1460 participants aged 65-90 years scheduled for elective total knee arthroplasty. Participants will be randomly assigned (1:1) to receive either active electroacupuncture (at GV24 and bilateral GB13 acupoints, 1 mA for 30 min before anesthesia induction; ETHICS AND DISSEMINATION: The protocol was approved by the Institutional Review Board of Fujian Provincial Hospital (K2023-02-004/02). All participating centers obtained ethics committee approval before enrollment. Written informed consent will be obtained from all participants. Results will be published in peer-reviewed journals, regardless of the outcome.
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