Evidence map›Paper›PMID 41034404›Full record

ArticleCancer gene therapy2025

New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene.

Amin Mirzaiebadizi, Mohammad Reza Ahmadian

Abstract read
In one paragraph

Article in Cancer gene therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amin MirzaiebadiziInstitute of Biochemistry and Molecular Biology II, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany. amin.mirzaiebadizi@hhu.de.ORCID 0000-0002-3340-586X
Mohammad Reza AhmadianInstitute of Biochemistry and Molecular Biology II, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany. reza.ahmadian@hhu.de.ORCID 0000-0002-2034-8894

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) AH 92/8-3
6 · The paper itself

Abstract

The RAC1

Indexed as

MelanomaMutationOncogenesrac1 GTP-Binding ProteinCell Line, TumorGuanine Nucleotide Exchange FactorsHumansSignal TransductionGuanine Nucleotide Exchange Factorsrac1 GTP-Binding ProteinRAC1 protein, human

Identifiers

PMID41034404
PMCPMC12702776

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.