Evidence map›Paper›PMID 41036046›Full record

ReviewSurgical neurology international2025

Elucidating the benefit of drug-eluting stent for symptomatic intracranial atherosclerotic stenosis: Meta-analysis of randomized controlled trials.

Cindy Thiovany Soetomo, Dewa Putu Wisnu Wardhana, Made Favian Budi Gunawan, Agung Bagus Sista Satyarsa, Rohadi Muhammad Rosyidi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cindy Thiovany SoetomoFaculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Indonesia.
Dewa Putu Wisnu WardhanaDepartment of Surgery, Division of Neurosurgery, Faculty of Medicine, Udayana University, Udayana University Hospital, Badung, Bali, Indonesia.
Made Favian Budi GunawanFaculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Indonesia.
Agung Bagus Sista SatyarsaDepartment of Surgery, Division of Neurosurgery, Faculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Indonesia.
Rohadi Muhammad RosyidiDepartment of Neurosurgery, Faculty of Medicine, Mataram University, West Nusa Tenggara Provincial General Hospital, Mataram, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intracranial atherosclerotic stenosis (ICAS) is a major global cause of stroke. Patient with high risk of recurring strokes despite standard medication therapy usually needs aggressive medical treatment such as self-expanding and balloon-expandable stents. Drug-eluting stents (DESs), with anti-vascular endothelial cell proliferation drugs, aim to inhibit smooth muscle cells proliferation and migration, providing a promising alternative to standard bare metal stents (BMS). This study compared the advantages and safety of DES to BMS in symptomatic ICAS patients. Methods: A comprehensive search was conducted through PubMed, Cochrane Central Register of Controlled Trials, and Science Direct in May 2024, adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Randomized trials comparing DES and BMS for symptomatic intracranial and vertebral artery stenosis were included in the study. Meta-analysis was carried out by RevMan software to analyze and odds ratio (OR) for primary and secondary outcomes. Results: Three randomized controlled trials ( Conclusion: Intravascular DES is more effective than BMS in lowering risk of ISR and incidence of ischemic stroke in symptomatic ICAS.

Indexed as

Bare metal stentDrug-eluting stentIn-stent restenosisIntracranial atherosclerotic disease

Identifiers

PMID41036046
PMCPMC12482777

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.