Evidence map›Paper›PMID 41036428›Full record

ArticleFrontiers in chemistry2025

Design, synthesis, antiproliferative assessments, and computational studies of new quinolin-2(1

Lamya H Al-Wahaibi, Hesham A Abou-Zied, Martin Nieger, Stefan Bräse, Bahaa G M Youssif, Hendawy N Tawfeek

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Lamya H Al-WahaibiDepartment of Chemistry, College of Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Hesham A Abou-ZiedMedicinal Chemistry Department, Faculty of Pharmacy, Deraya University, Minia, Egypt.
Martin NiegerDepartment of Chemistry, University of Helsinki, Helsinki, Finland.
Stefan BräseInstitute of Biological and Chemical Systems, IBCS-FMS, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Bahaa G M YoussifDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Hendawy N TawfeekChemistry Department, Faculty of Science, Minia University, El Minia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: A novel series of quinolin-2(1 Methods: Structural elucidation was achieved through IR, NMR, mass spectrometry, elemental analysis, and single-crystal X-ray crystallography. The synthesized compounds were screened for antiproliferative activity against four human cancer cell lines. Results and Discussion: Compound

Indexed as

anticancerDFTEGFRHER-2kinasesquinolineX-ray

Identifiers

PMID41036428
PMCPMC12481029

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.