Evidence map›Paper›PMID 41040585›Full record

ArticleJournal of dental sciences2025

A scientometric study on Wnt and Notch signaling pathways in oral potentially malignant disorders and oral cancer.

Xiaoliang Luo, Yiwen Deng, Hao Wu

Abstract read
In one paragraph

Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaoliang LuoDepartment of Periodontology and Oral Mucosa, Changsha Stomatological Hospital, School of Dental Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Yiwen DengDepartment of Oral Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hao WuDepartment of Periodontology and Oral Mucosa, Changsha Stomatological Hospital, School of Dental Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Accumulating evidence indicates that aberrant activation of certain cellular signaling pathways occurs during the development and progression of oral cancer. The purpose of this study was to analyze the scientometric characteristics of Wnt and Notch pathways in oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC). Materials and methods: All the papers on Wnt and Notch pathways in OPMD/OSCC were comprehensively retrieved from the Scopus database. Results: A total of 301 and 169 papers on Wnt and Notch signaling pathway in the field of OPMD/OSCC were retrieved, respectively. As for Wnt pathway in OPMD/OSCC research, distinctive keywords included canonical Wnt signaling, β-catenin, CTNNB1 protein, cyclin D1, frizzled protein, Myc, Bcl-2, transcription factor, DNA methylation, long noncoding RNA, and microRNA. As for Notch pathway, distinctive keywords of bioresearch aspect included cancer stem cell, angiogenesis, genetic association, oncogene, and Jagged1. There were the same common keywords of bioresearch aspect, such as metabolism, genetics, signal transduction, apoptosis, cell proliferation, carcinogenesis, tumor marker, epithelial mesenchymal transition, protein function, drug screening, and gene mutation. Conclusion: This study for the first time elucidated the scientometric characteristics of all the publications on Wnt and Notch pathways in OPMD/OSCC, and would provide new insights for researchers to delve into the mechanisms of Wnt and Notch related OPMD/OSCC and translate into clinical studies.

Indexed as

BibliometricsMolecular mechanismsNotchOral cancerOral potentially malignant disordersWnt/β-catenin

Identifiers

PMID41040585
PMCPMC12485456

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.