Evidence map›Paper›PMID 41042354›Full record

ArticleFish physiology and biochemistry2025

Investigating the immunomodulatory and haemato-protective roles of curry leaf ethanolic extract (Murraya koenigii) in Labeo rohita fingerlings Infected with Aeromonas hydrophila.

Sourabh Debbarma, Bagthasingh Chrisolite, Panchavarnam Sivasankar, P Senthil Kumar, V Senthil Kumar, N Daniel, Palaniappan Subash, Muthumariappan Selvamagheswaran, Mohamed Mansoor, Magesh Kumar Paulraj

Abstract read
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In one paragraph

Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. DietaryFrontiers in immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sourabh DebbarmaDepartment of Fish Pathology and Health Management, Fisheries College and Research Institute, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Thoothukudi, Tamil Nadu, 628008, India. salchangdb@gmail.com.
Bagthasingh ChrisoliteDepartment of Fish Pathology and Health Management, Fisheries College and Research Institute, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Thoothukudi, Tamil Nadu, 628008, India. chrisolite@tnfu.ac.in.
Panchavarnam SivasankarDepartment of Fish Pathology and Health Management, Fisheries College and Research Institute, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Thoothukudi, Tamil Nadu, 628008, India.
P Senthil KumarDepartment of Veterinary Pharmacology and Toxicology, Veterinary College and Research Institute, Orathanadu, Thanjavur, Tamil Nadu, 614625, India.
V Senthil KumarICAR-Krishi Vigyan Kendra(KVK), Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Nagapattinam, Sikkal-611108, India.
N DanielKanyakumari Ganapathipuram Centre for Sustainable Aquaculture (KKG CeSA), Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Thoothukudi, Tamil Nadu, 628008, India.
Palaniappan SubashDepartment of Fish Pathology and Health Management, Fisheries College and Research Institute, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Thoothukudi, Tamil Nadu, 628008, India.
Muthumariappan SelvamagheswaranDepartment of Fish Pathology and Health Management, Fisheries College and Research Institute, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Thoothukudi, Tamil Nadu, 628008, India.
Mohamed MansoorDepartment of Fish Pathology and Health Management, Fisheries College and Research Institute, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Thoothukudi, Tamil Nadu, 628008, India.
Magesh Kumar PaulrajDepartment of Fish Pathology and Health Management, Fisheries College and Research Institute, Tamil Nadu Dr. J. Jayalalithaa Fisheries University, Thoothukudi, Tamil Nadu, 628008, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aeromonas hydrophila is a highly virulent pathogen that causes substantial mortality in Labeo rohita fingerlings. In our present study, phytochemical analysis of curry leaf (Murraya koenigii) confirmed the presence of bioactive compounds such as alkaloids, phenolics, flavonoids, and terpenoids, known for their potent antimicrobial and immunomodulatory properties. This study evaluates the immunomodulatory and haemato-protective effects of curry leaf (Murraya koenigii) ethanolic extract (CLEE) against Aeromonas hydrophila infection in Labeo rohita, focusing on haematological, biochemical, and immunological parameters. In infection trials, survival rates were higher for feeds treated with 1 g, 2 g, and 3 g of CLEE were 46.67%, 68.89%, and 66.67%, respectively, compared to 36.67% in the bacterial control group. Haematological results showed a significant dose-dependent increase in red blood cell (RBC) count, haemoglobin, and white blood cell (WBC) count. The CLEE 2 g and CLEE 3 g groups had significantly (P < 0.05) higher RBC counts of 1.08 ± 0.01

Indexed as

Aeromonas hydrophilaCyprinidaeFish DiseasesGram-Negative Bacterial InfectionsMurrayaPlant ExtractsAnimal FeedAnimalsEthanolPlant LeavesEthanolPlant ExtractsAeromonas hydrophilaAntioxidant enzymeBioactive compoundsCurry leaf (Murraya koenigii)Labeo rohita etc.Soxhlet extraction

Identifiers

PMID41042354

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.