SynthesisJournal of Alzheimer's disease : JAD2025
Epidemiological and economic burden of dementia in the Middle East and North African region.
Synthesis in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundDementia is a global health challenge projected to nearly triple by 2050, especially in the Middle East and North Africa (MENA). Understanding its epidemiology and economic impact is vital for public health planning.ObjectiveThis systematic review aims to synthesize evidence on dementia, particularly the prevalence of Alzheimer's disease, its economic burden, and caregiving in MENA countries, to facilitate informed policy-making and effective resource allocation.MethodsWe performed a random-effects meta-analysis to determine the pooled prevalence of dementia from studies published between 2014 and 2025 in PubMed, Scopus, and Google Scholar. Two reviewers independently selected and extracted data, assessing bias risk with the Cochrane Risk of Bias Tool. This review followed PRISMA 2020 guidelines and is registered in PROSPERO (CRD42024550935).ResultsTwelve studies met the criteria, showing dementia prevalence in MENA countries from 1.1% to 7.9%, with higher rates in Iran, Israel, and Lebanon, highlighting the need for public health campaigns. The annual estimated cost for those aged 50 and older is about USD 8.18 billion. Caregiving mainly fell to female family members, with larger socioeconomic impacts than in other regions.ConclusionsDementia is a growing public health concern in MENA, requiring improved healthcare infrastructure, increased caregiver support, and targeted research to fill knowledge gaps.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.