Evidence map›Paper›PMID 41042968›Full record

ArticleJournal of clinical neurophysiology : official publication of the American Electroencephalographic Society2026

An Electric Source Imaging Approach Demonstrating Diagnostic Value of Nasopharyngeal Electrodes in Temporal Lobe Epilepsy.

Yun Ho Choi, Taeik Jang, Soo Hwan Yim, Kyoung Heo

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Article in Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yun Ho ChoiDepartment of Neurology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Taeik JangDepartment of Neurology, Ulsan University, College of Medicine, Gangneung Asan Hospital, Gangneung, Republic of Korea; and.
Soo Hwan YimDepartment of Neurology, Ulsan University, College of Medicine, Gangneung Asan Hospital, Gangneung, Republic of Korea; and.ORCID 0000-0003-2948-9244
Kyoung HeoDepartment of Neurology, Epilepsy Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the different regions covered by nasopharyngeal (NPEs) and anterior temporal (anterior temporal electrodes [ATEs]) electrodes in assessing temporal lobe epilepsy, to overcome the limitations of the 10 to 20 electroencephalography (EEG) in diagnosing the basal and mesial temporal regions.

methodsEEG data from 229 patients diagnosed with temporal lobe epilepsy were simultaneously analyzed with attached NPEs and ATEs. In case of discrepancies in EEG interpretation, a consensus interpretation was reached among three epilepsy experts. Spike detection was conducted using the Curry9 program for secondary analysis of electric source localization, with source location performed using standard brain MRI data.

resultsIn total, 2,721 interictal epileptiform discharges (IEDs) from 175 patients were analyzed. Of these, 734 IEDs from 48 patients were detected exclusively with NPEs, while 1,987 IEDs from 127 patients were detected simultaneously by both NPEs and the standard international 10 to 20 electrodes system supplemented with ATEs, respectively. The former IEDs exhibited clustering dipoles in the basal and mesial temporal regions, while the latter were localized solely to the frontotemporal and lateral temporal regions.

conclusionsNasopharyngeals can identify IEDs in the mesial and basal temporal region that cannot be detected by ATEs. Nasopharyngeals offer additional diagnostic value in regions not confirmed by the existing 10 to 20 EEG electrode system, including those covered by ATE.

Indexed as

ElectroencephalographyEpilepsy, Temporal LobeNasopharynxAdolescentAdultChildElectrodesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedTemporal LobeYoung AdultEEGElectric source imagingNasopharyngeal electrodeTemporal lobe epilepsy

Identifiers

PMID41042968
PMCPMC13124259

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