Evidence map›Paper›PMID 41044104›Full record

ArticleScientific reports2025

Fermented pickles improve gut microbiota and immune profile in women in a community trial in rural Pakistan.

Sumbal H Hafeez, Aqsa Khalid, Sheraz Ahmed, Fayaz Umrani, Abdul Khaliq Qureshi, Kumail Ahmed, Fariha Shaheen, Aneeta Hotwani, Furqan Kabir, Sean R Moore and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sumbal H HafeezBiological & Biomedical Sciences, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Aqsa KhalidDepartment of Cellular and Molecular Pathology, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Sheraz AhmedBiological & Biomedical Sciences, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Fayaz UmraniDepartment of Community Health Sciences, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Abdul Khaliq QureshiDepartment of Community Health Sciences, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Kumail AhmedDepartment of Paediatrics and Child Health, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Fariha ShaheenDepartment of Paediatrics and Child Health, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Aneeta HotwaniDepartment of Paediatrics and Child Health, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Furqan KabirDepartment of Paediatrics and Child Health, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Sean R MooreDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Syed Asad AliDepartment of Community Health Sciences, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan.
Junaid IqbalDepartment of Paediatrics and Child Health, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan. junaid.iqbal@aku.edu.
Najeeha Talat IqbalDepartment of Paediatrics and Child Health, Aga Khan University, Stadium Road, Karachi, 74800, Pakistan. najeeha.iqbal@aku.edu.

Funding

Pediatric Infectious Diseases, Enteric Health and Malnutrition in Pakistan (PIDEMP) Research Training ProgramD43TW007585 · FIC · AGA KHAN UNIVERSITY (PAKISTAN) · PI ALI, SYED ASAD, MOORE, SEAN RYAN · 2006 to 2024
$3.7M
Bill & Melinda Gates Foundation INV- 033567FIC NIH HHS D43 TW007585National Institute of Health's Fogarty International Center 5D43TW007585-13
6 · The paper itself

Abstract

A gut microbiome-targeted diet can potentially mitigate chronic diseases, including malnutrition. In a prospective 12-week intervention trial, we evaluated the effects of six different plant-based fermented pickles (~ 50 g/day) on clinical, inflammatory, and gut microbiota parameters in a cohort of women (n = 230) in a rural setting with a high prevalence of undernutrition. Blood was collected at two, whereas stool was collected at three timepoints. Among fecal biomarkers, myeloperoxidase (MPO), Lipocalin-2 (LCN2), and 16S rRNA gene sequencing were measured at baseline, 8

Indexed as

Fermented FoodsGastrointestinal MicrobiomeAdultBiomarkersFecesFemaleHumansLipocalin-2Middle AgedPakistanPeroxidaseProspective StudiesRNA, Ribosomal, 16SRural PopulationBiomarkersLipocalin-2PeroxidaseRNA, Ribosomal, 16S

Identifiers

PMID41044104
PMCPMC12494867

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.