ArticleNature communications2025
Creative experiences and brain clocks.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Trial
- Linking the exposome to the brain-behaviour phenotype.Nature reviews. Neuroscience · 2026Review
- Source-space EEG alpha activity reveals brain age gaps due to neurodegeneration and disparity.Communications biology · 2026Article
- Review
- Brain Structural Covariance Networks in Long-Term First-Person Shooter and Multiplayer Online Battle Arena Players: Cross-Sectional Study.JMIR serious games · 2026Article
- The exposome of brain aging across 34 countries.Nature medicine · 2026Article
- Pathways to resilience: relationships between cognitive reserve, psychological debt, and Alzheimer's disease biomarkers.Alzheimer's research & therapy · 2026Article
- Childhood adversities and the exposome in dementia risk and brain health.Current opinion in psychiatry · 2026Review
- Expotype-phenotype resilience and multimodal aging clocks.Clinical and translational medicine · 2026Article
- Computational whole-body-exposome models for global precision brain health.Nature communications · 2025Article
- Brain Myelin Covariance Networks: Gradients, Cognition, and Higher-Order Landscape.Behavioral sciences (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
50 authors.
Funding
Abstract
Creative experiences may enhance brain health, yet metrics and mechanisms remain elusive. We characterized brain health using brain clocks, which capture deviations from chronological age (i.e., accelerated or delayed brain aging). We combined M/EEG functional connectivity (N = 1,240) with machine learning support vector machines, whole-brain modeling, and Neurosynth metanalyses. From this framework, we reanalyzed previously published datasets of expert and matched non-expert participants in dance, music, visual arts, and video games, along with a pre/post-learning study (N = 232). We found delayed brain age across all domains and scalable effects (expertise>learning). The higher the level of expertise and performance, the greater the delay in brain age. Age-vulnerable brain hubs showed increased connectivity linked to creativity, particularly in areas related to expertise and creative experiences. Neurosynth analysis and computational modeling revealed plasticity-driven increases in brain efficiency and biophysical coupling, in creativity-specific delayed brain aging. Findings indicate a domain‑independent link between creativity and brain health.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.