ArticleBMC veterinary research2025
In vivo antiparasitic activity of biogenic Iron nanoparticles on ectoparasitic branchiuran, Argulus siamensis in Labeo rohita and effect on parasite ion channel genes.
Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Charting the Future: Advanced Technologies for Sustainable Parasite Control in Aquaculture.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArgulosis, caused by Argulus, is a significant parasitic disease affecting freshwater aquaculture, leading to severe economic losses and compromised fish health. This study investigates the antiparasitic efficacy of green-synthesized iron oxide nanoparticles (IONPs) synthesized using Bauhinia racemosa leaf extract against A. siamensis in Labeo rohita. The nanoparticles exhibited a spherical morphology with an average size of 157.60 ± 41.59 nm and a zeta potential of -11.3 mV, ensuring moderate stability.
resultThe in vivo trial confirmed the antiparasitic efficacy of biogenic IONPs, with 100% parasite removal at 2.25 mg mL⁻¹ within four days of bath treatment. Acute toxicity studies in Labeo rohita established a 96-hour LC₅₀ of 4.786 mg mL⁻¹, while the therapeutic index (TI) was calculated as 3.31, indicating a moderate safety margin. Gene expression analysis revealed significant upregulation of ion channel genes - GABA, ICA1, ICA4, and NTR, indicating a neurotoxic effect of IONPs on parasites.
conclusionsOverall, biosynthesized IONPs present a promising alternative for controlling Argulus siamensis, demonstrating strong antiparasitic effects with manageable toxicity. Further studies on optimizing nanoparticle formulations and minimizing environmental risks are recommended to enhance their application in sustainable aquaculture.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.