Evidence map›Paper›PMID 41047748›Full record

ArticleVeterinary ophthalmology2026

Antimicrobial Activity of Ultraviolet C Light as a Potential Novel Treatment for Moraxella bovis Infection-An In Vitro Study.

Bactelius Turicea, Dipak K Sahoo, Rachel A Allbaugh, Chloe C Stinman, Melissa A Kubai

Abstract read
In one paragraph

Article in Veterinary ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bactelius TuriceaDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.ORCID https://orcid.org/0000-0001-6765-5800
Dipak K SahooDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.ORCID https://orcid.org/0000-0003-3748-3395
Rachel A AllbaughDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
Chloe C StinmanVeterinary Diagnostic Laboratory, Iowa State University, Ames, Iowa, USA.
Melissa A KubaiDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.ORCID https://orcid.org/0000-0003-0091-2037

Funding

Iowa State University VCS SG2701210
6 · The paper itself

Abstract

objectiveTo investigate the antimicrobial effect of 275 nm wavelength ultraviolet C (UV-C) light on M. bovis using an affordable, broadly available modified handheld device and to determine if photoreactivation plays a role in bacterial resistance to UV-C.

methodsUV-C therapy (UVCT) was evaluated in vitro using triplicates of 3 M. bovis isolates from clinical cases. The UVCT was performed at a distance of 10, 15, and 20 mm with 1 or 2 doses (4 h apart) for 5, 15, or 30 s (s); the photoreactivation plates were exposed to 12 h of light at different times (T): T

resultsIn vitro results showed all plates treated with UVCT had a 100% bactericidal effect for all the isolates with a single dose of 15 s at a 10 mm distance. At 15 and 20 mm of distance, 2 doses, 4 h apart, were needed for the same effect, or a single dose of 30 s, which had an 88.8% bactericidal effect. No bacterial regrowth was noticed macroscopically after exposure of the treated plates to artificial light at any time point.

conclusionsThe therapeutic potential for killing M. bovis was confirmed in vitro for all tested isolates using a single exposure of 15 s. UVCT can reduce the need for antibiotics, thereby shortening withdrawal periods for animal-derived food products, having a major impact on the cattle industry. Photoreactivation might not play a role in bacterial resistance to UV-C. While safety studies are underway, clinical trials are warranted.

Indexed as

Cattle DiseasesMoraxella bovisMoraxellaceae InfectionsUltraviolet RaysAnimalsCattlecorneal UV‐C therapyinfectious bovine keratoconjunctivitisMoraxella bovisphotoreactivationpink eye diseaseUV‐C light

Identifiers

PMID41047748
PMCPMC12963516

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.