ArticleFrontiers in plant science2025
Tissue-specific biosynthesis and regulation of alkaloids, flavonoids, and terpenoids in fenugreek (
Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Article
- Escherichia coli DH5α-loaded fenugreek extract: an effective anticancer combination against human breast cancer cell lines.Applied microbiology and biotechnology · 2026Article
- Identification of MultipleInternational journal of molecular sciences · 2026Article
- Integrated transcriptomic and metabolomic profiling reveals a JAZ-transcription factor network governing MeJA-induced flavonoid accumulation inFrontiers in plant science · 2026Article
- Integrative phytochemical profiling andFrontiers in nutrition · 2026Article
- Integrative metabolomic and transcriptomic analyses reveal the regulatory mechanisms underlying the biosynthesis of flavonoid and terpenoid metabolites in different tissues ofFrontiers in plant science · 2026Article
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Authors and funding
5 authors.
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Abstract
Introduction: Fenugreek ( Methods: This study employed metabolomics and transcriptomics to analyze metabolite profiles and gene expression in fenugreek roots, stems, and leaves. Using UPLC-MS/MS, we identified 2,124 metabolites, and full-length transcriptome sequencing alongside RNA-seq analysis revealed tissue-specific differentially expressed genes (DEGs). Results: Our analysis revealed distinct tissue-specific accumulation patterns of alkaloids, flavonoids, and terpenoids. The roots were identified as the primary site for the biosynthesis of these secondary metabolites. Multi-omics integration pinpointed key biosynthetic genes, such as Discussion: This study enhances understanding of metabolic regulations in fenugreek and offers molecular resources for medicinal plant breeding.
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