Evidence map›Paper›PMID 41050155›Full record

ReviewBioscience of microbiota, food and health2025

Gut microbiome in adult Asians with obesity, type 2 diabetes mellitus, and a combination of obesity and type 2 diabetes mellitus.

Nadia Widjaja, Christine Agustina, Felicia Felicia, Frederick Wijaya, Jacqueline Limanjaya, Adi Yulandi, Diana Elizabeth Waturangi, Stefeny Theresia Simatupang, Santi Tan, Raymond Rubianto Tjandrawinata

Abstract readReview
In one paragraph

Review in Bioscience of microbiota, food and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nadia WidjajaFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, South Jakarta, DKI Jakarta 12930, Indonesia.
Christine AgustinaFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, South Jakarta, DKI Jakarta 12930, Indonesia.
Felicia FeliciaFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, South Jakarta, DKI Jakarta 12930, Indonesia.
Frederick WijayaFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, South Jakarta, DKI Jakarta 12930, Indonesia.
Jacqueline LimanjayaFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, South Jakarta, DKI Jakarta 12930, Indonesia.
Adi YulandiFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, South Jakarta, DKI Jakarta 12930, Indonesia.
Diana Elizabeth WaturangiFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, South Jakarta, DKI Jakarta 12930, Indonesia.
Stefeny Theresia SimatupangDexa Omic Sciences (Dexomics), Dexa Medica, South Tangerang, Banten 15224, Indonesia.
Santi TanDexa Omic Sciences (Dexomics), Dexa Medica, South Tangerang, Banten 15224, Indonesia.
Raymond Rubianto TjandrawinataFaculty of Biotechnology, Atma Jaya Catholic University of Indonesia, South Jakarta, DKI Jakarta 12930, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity and type 2 diabetes (T2D) are two of the most common health problems in the world, particularly in adult Asians, with a significant impact on morbidity and mortality. Numerous studies have revealed that the gut microbiome of people with obesity and T2D differs significantly from those of healthy people. Those who suffer from certain illnesses often encounter disruption in their gut microbiome, leading to a decrease in richness diversity and diminished microbial activity. This disruption can also result in the loss of the gut mucosal barrier, increased gut permeability, and most likely, the development of a leaky gut. Recent studies have also emphasized the essential role of the gut microbiome in these conditions. However, conflicting findings were found between one study and another investigation. Therefore, this paper aims to provide an overview of gut microbiome characteristics in adult Asians with obesity, T2D, and the combination of both. In addition, this paper elaborates on the current understanding regarding the association of the gut microbiome with health status, thereby serving as a foundation for developing probiotics or prebiotics to modulate the gut microbiome and improve metabolic health.

Indexed as

adult Asiansgut microbiomeobesitytype 2 diabetes

Identifiers

PMID41050155
PMCPMC12490873

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.