Evidence map›Paper›PMID 41053560›Full record

ArticleBMC cardiovascular disorders2025

Inequity, workload, and external factors: a descriptive study on high-intensity statin prescriptions for patients with clinical cardiovascular disease and at high risk for cardiovascular disease.

Liberty Nguyen, Ethlyn Voorhies, Christy Jesme, Anya Deleeuw, Jean Marie McGowan, Abe Sahmoun, Laura Nichols

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liberty NguyenUniversity of North Dakota School of Medicine and Health Sciences, 1301 North Colombia Road, Grand Forks, ND, 58202, USA. nguy6133@umn.edu.
Ethlyn VoorhiesUniversity of North Dakota School of Medicine and Health Sciences, 1301 North Colombia Road, Grand Forks, ND, 58202, USA.
Christy JesmeUniversity of North Dakota School of Medicine and Health Sciences, 1301 North Colombia Road, Grand Forks, ND, 58202, USA.
Anya DeleeuwUniversity of North Dakota School of Medicine and Health Sciences, 1301 North Colombia Road, Grand Forks, ND, 58202, USA.
Jean Marie McGowanMayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Abe SahmounDepartment of Internal Medicine, University of North Dakota School of Medicine and Health Sciences, 1919 Elm Street N, Fargo, ND, 58102, USA.
Laura NicholsDepartment of Internal Medicine, University of North Dakota School of Medicine and Health Sciences, 1919 Elm Street N, Fargo, ND, 58102, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite guidelines for statin use to reduce atherosclerotic cardiovascular disease (ASCVD) from the American College of Cardiology and American Heart Association (ACC/AHA) and quality measures from the Centers for Medicare and Medicaid Services (CMS), inconsistencies in guideline adherence persist. While there are studies examining associations of individual factors with statin prescriptions, there is a paucity of literature considering multiple factors.

methodsWe conducted a cross-sectional, retrospective review of 20,923 medical charts of patients diagnosed with ASCVD, low-density lipoprotein cholesterol (LDL-c) ≥ 190 mg/dL, or ASCVD risk ≥ 20%, aged 40 to 75 years old. Statin prescribing rates were as follows: high-intensity statins (33.7%), low- or medium-intensity statins (33.5%), and no statin (32.8%).

resultsSex significantly affected high-intensity statin prescribing, as 35.2% of men and 30.3% of women received a high-intensity statin (p < 0.0001). Race significantly affected any statin prescribing as 67.4% of White patients, 59.0% of Black patients, and 64.1% of American Indian/Alaska Native patients received any statin prescription (p = 0.0074). The mean age for patients prescribed a high-intensity statin was also significantly lower (64.8 years) than those not (66.6 years) (p < 0.001). Increased number of appointments was statistically significant for increased use of high-intensity statins (p = 0.0001) and any statin (p = 0.0001). Female primary care providers (PCPs) had a prescribing rate of 71.0% while male PCPs had a rate of 68.5% for any statin (p = 0.0005).

conclusionsWe found that adherence to ACC/AHA and CMSguidelines remains incomplete and highlights several factors contributing to lower likelihood of statin prescription including patient and PCP demographics.

Indexed as

Cardiovascular DiseasesDyslipidemiasHealthcare DisparitiesHydroxymethylglutaryl-CoA Reductase InhibitorsPractice Patterns, Physicians'WorkloadAdultAgedCross-Sectional StudiesDrug PrescriptionsFemaleGuideline AdherenceHeart Disease Risk FactorsHumansMaleMiddle AgedHydroxymethylglutaryl-CoA Reductase InhibitorsCardiovascular diseaseQuality measuresStatin prescription

Identifiers

PMID41053560
PMCPMC12502201

What Socratic holds

Texttitle and abstract
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.