Evidence map›Paper›PMID 41054419›Full record

ArticleiLIVER2025

AI-driven multimodal fusion of tongue images and clinical indicators for identifying MAFLD patients at risk of coronary artery disease: An exploratory study.

Jingjing Zhang, Song Feng, Jian Xue, Chao Zhou, Shuangnan Fu, Pengcheng Liu, Zhaoyun He, Man Gong, Hui Feng, Shuangnan Zhou and 1 more

Abstract read
In one paragraph

Article in iLIVER, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jingjing ZhangSenior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Song FengDepartment of Ultrasound, Senior Department of Oncology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Jian XueSenior Department of Cardiology, The Sixth Medical Center of Chinese PLA General Hospital, Beijing 100048, China.
Chao ZhouSenior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Shuangnan FuSenior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Pengcheng LiuSenior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Zhaoyun HeSenior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Man GongSenior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Hui FengDepartment of Ultrasound, Senior Department of Oncology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Shuangnan ZhouSenior Department of Infectious Disease, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Ning ZhangSenior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Metabolic dysfunction-associated fatty liver disease (MAFLD) is associated with coronary artery disease (CAD), but existing risk assessment tools lack precision and scalability. We developed an AI-driven multimodal framework integrating traditional Chinese medicine (TCM) tongue-based diagnosis with clinical biomarkers to stratify CAD risk in MAFLD. Methods: In this cross-sectional study with prospective data collection, which comprised 1073 MAFLD patients stratified by CAD status (MAFLD without CAD, Results: The coexistence of CAD was associated with significantly higher rates of hypertension, diabetes, and familial cardiovascular history in patients with MAFLD ( Conclusion: Our AI-driven dual-model framework addresses the critical unmet need for CAD identification in MAFLD patients, providing a community-scalable screening tool (Model-1) and a precision clinical assessment model (Model-2), while offering empirical support for TCM tongue diagnosis. Pending external validation to confirm its generalizability, this approach may serve as a cost-efficient non-invasive screening strategy for this high-risk population.

Indexed as

Artificial intelligenceCoronary artery diseaseMetabolic dysfunction-associated fatty liver diseaseMulti-modal fusionTongue image

Identifiers

PMID41054419
PMCPMC12496237

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.