Evidence map›Paper›PMID 41054499›Full record

ArticleJournal of asthma and allergy2025

Minimal Clinically Important Difference of the Taiwan Smell Test in Patients with Bilateral Chronic Rhinosinusitis and Nasal Polyps Post-Sinus Surgery.

Pei-Wen Wu, Ping-Hung Shen, Yun-Shien Lee, Po-Hung Chang, Chi-Che Huang, Chien-Chia Huang

Abstract read
In one paragraph

Article in Journal of asthma and allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pei-Wen WuDivision of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
Ping-Hung Shen *Department of Otolaryngology, Kuang Tien General Hospital, Taichung, Taiwan.ORCID 0000-0003-3762-8291
Yun-Shien LeeGenomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID 0000-0001-9617-335X
Po-Hung ChangDivision of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
Chi-Che HuangDivision of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
Chien-Chia Huang *Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0003-4188-3498

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The impairment of smell has become a crucial evaluation in determining disease severity, control status, and therapeutic response in patients with chronic rhinosinusitis and nasal polyps (CRSwNP). This study aimed to evaluate the minimal clinically important difference (MCID) of the Taiwan Smell Identification Test (TWSIT) in patients with CRSwNP undergoing endoscopic sinus surgery (ESS). Methods: Patients with bilateral CRSwNP who underwent ESS were prospectively enrolled. The 22-item Sino-Nasal Outcome Test questionnaire and TWSIT were utilized to evaluate both subjective and objective olfactory function before surgery and 3 months postoperatively. Results: Eighty-six patients with bilateral CRSwNP (53 males, 33 females) were enrolled. Moderate-to-high correlations were observed between the subjective smell loss scores and baseline TWSIT scores Conclusion: This study established that a TWSIT score change ≥ 7 is clinically meaningful for patients with CRSwNP following sinus surgery. Bridging objective test results with subjective perceptions can help clinicians identify patients with suboptimal therapeutic outcomes and guide decisions regarding additional treatments.

Indexed as

chronic rhinosinusitisendoscopic sinus surgeryminimal clinically important differencenasal polypsTaiwan smell identification test

Identifiers

PMID41054499
PMCPMC12497362

What Socratic holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.