Evidence map›Paper›PMID 41059146›Full record

ArticleRadiology advances2024

Pathologic outcome of incidentally detected tracer-avid lesions in

Darryl Mar, Devan Diwanji, Blair Lowery, Li Zhang, Thomas A Hope, Spencer C Behr, Robert R Flavell

Abstract read
In one paragraph

Article in Radiology advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Darryl MarDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, United States.ORCID https://orcid.org/0000-0002-8471-9930
Devan DiwanjiDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, United States.
Blair LoweryDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, United States.
Li ZhangDepartment of Medicine, University of California, San Francisco, CA 94143, United States.
Thomas A HopeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, United States.ORCID https://orcid.org/0000-0002-2228-5823
Spencer C BehrDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, United States.ORCID https://orcid.org/0000-0001-9400-0543
Robert R FlavellDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, United States.ORCID https://orcid.org/0000-0002-8694-1199

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prostate-specific membrane antigen (PSMA) PET is effective in identifying prostate cancer metastases. However, PSMA PET uptake has also been described in other lesions, including nonprostate malignancies and benign processes. Purpose: To identify causes of unexpected radiopharmaceutical accumulation on PSMA PET. Materials and Methods: A total of 2,054 study reports representing 1,873 unique patients who had undergone Results: In 48 patients, the PSMA ligand-avid incidental lesions revealed 19 cases of second malignancies, 17 cases of prostate cancer, and 13 cases of benign lesions. The most common lesion locations were lung (14), thyroid (14), lymph nodes (8), and bowel (4). Benign lesions exhibited lower molecular imaging PSMA scores (median: 1; interquartile range [IQR]: 1.00-1.25; Conclusion: Features that influence the probability of an incidental lesion representing a malignancy include lesion location, reason for the PSMA PET/CT study, and associated imaging features (size, standardized uptake value maximum, and molecular imaging PSMA score).

Indexed as

molecular imagingPET/CTprostate cancerprostate specific membrane antigen (PSMA)

Identifiers

PMID41059146
PMCPMC12429197

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.