Evidence mapPaperPMID 41059513Full record

ArticleFrontiers in neurology2025

The predictive value of triglyceride-glucose index on early neurological functional improvement in non-diabetic patients with acute ischemic stroke undergoing intravenous thrombolysis.

Furong Li, Xiaowen Sui, Xin Pan, Jun Li, Yan Gao, Dandan Shi, Hongling Zhao, Dong Chen

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [A prediction model for early neurological improvement after intravenous thrombolysis in patients with acute ischemic stroke].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Furong LiStroke Center, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Xiaowen SuiNeurology Department, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Xin PanNeurology Department, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Jun LiStroke Center, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Yan GaoStroke Center, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Dandan ShiStroke Center, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Hongling ZhaoStroke Center, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Dong ChenNeurosurgery Department, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the predictive role of the triglyceride-glucose index (TyG index) on the early neurological improvement in non-diabetic patients with acute ischemic stroke (AIS) undergoing alteplase intravenous thrombolysis (IV-rtPA). Methods: This study included 490 AIS patients without diabetes, whose time from onset to hospital time ≤3 h undergoing IV-rtPA in the Stroke Center of our hospital from September 2023 to September 2024 through the Stroke Emergency Map Management Platform in Dalian City. According to the National Institutes of Health Stroke Scale (NIHSS) score at 24 h after IVT, the patients were divided into early neurological improvement (ENI) group ( Results: (1) In the ENI group, blood glucose (FBG), triglycerides (TG), TyG index, and baseline NIHSS score were significantly lower than those in the non-ENI group ( Conclusion: The TyG index, baseline NIHSS score, and the combined variable (Y) are predictors of early neurological improvement, with the combined variable (Y) exhibiting a higher predictive efficiency.

Indexed as

acute ischemic strokeearly neurological improvementintravenous thrombolysisnon-diabetic patientstriglyceride-glucose index

Identifiers

PMID41059513
PMCPMC12497599

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.