Evidence map›Paper›PMID 41062056›Full record

Trial reportResuscitation2025

Single-arm feasibility trial of a resilience intervention for cardiac arrest survivors and their family caregivers, Recovering Together after Cardiac Arrest.

Alexander M Presciutti, Danielle La Camera, Sarah M Perman, Jonathan Elmer, Michael W Donnino, Ona Wu, Robert A Parker, Ana-Maria Vranceanu

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Resuscitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06517394 (Open Pilot Trial of a Dyadic Mind-body Program for Cardiac Arrest Survivors and Their Caregivers), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06517394 nacompletednot on this map

Open Pilot Trial of a Dyadic Mind-body Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest

TypeinterventionalSponsorMassachusetts General HospitalRan2024 to 2025Enrolled14ConditionsEmotional Distress, Cardiac ArrestArmsRecovering Together after Cardiac Arrest
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander M PresciuttiCenter for Health Outcomes and Interdisciplinary Research, Department of Psychiatry, Massachusetts General Hospital, United States; Department of Psychiatry, Harvard Medical School, United States. Electronic address: apresciutt@mgh.harvard.edu.
Danielle La CameraCenter for Health Outcomes and Interdisciplinary Research, Department of Psychiatry, Massachusetts General Hospital, United States.
Sarah M PermanDepartment of Emergency Medicine, Yale School of Medicine, United States.
Jonathan ElmerDepartments of Emergency Medicine, Critical Care Medicine, and Neurology, University of Pittsburgh, School of Medicine, United States.
Michael W DonninoCenter for Resuscitation Science, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, United States; Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, United States.
Ona WuAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, United States; Department of Radiology, Harvard Medical School, United States.
Robert A ParkerDepartment of Medicine, Harvard Medical School, United States.
Ana-Maria VranceanuCenter for Health Outcomes and Interdisciplinary Research, Department of Psychiatry, Massachusetts General Hospital, United States; Department of Psychiatry, Harvard Medical School, United States.

Funding

Recovering Together after Cardiac Arrest: A dyadic mind-body intervention for emotional distress in cardiac arrest survivors and their informal caregiversK23AT012487 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI Alex M. Presciutti · 2023 to 2026
$677k
NCCIH NIH HHS K23 AT012487NCCIH NIH HHS L30 AT012564
6 · The paper itself

Abstract

backgroundEmotional distress is common in cardiac arrest (CA) survivors and their family caregivers and undermines long-term health and quality of life. To address this, we adapted a resilience intervention for survivors and their caregivers, entitled Recovering Together after Cardiac Arrest (RT-CA).

methodsWe conducted a single-arm feasibility trial of RT-CA between 09/2024-03/2025. We enrolled dyads of consecutively admitted CA survivors at Massachusetts General Hospital and their primary family caregivers. INCLUSION CRITERIA: adult English speakers, survivors must have ability to meaningfully participate (Short Form Mini Mental State Exam ≥5), one dyad member must have emotional distress (≥8 on either subscale of the Hospital Anxiety and Depression Scale [HADS]). PROCEDURE: Dyads participated in six weekly sessions with a clinical psychologist focused on building mindfulness and coping skills. Feasibility outcomes were feasibility of recruitment, assessments, adherence; acceptability outcomes were satisfaction, credibility, expectancy. Dyads completed pre- and post-test psychosocial measures and participated in exit interviews. We calculated frequencies and proportions of our outcomes, conducted exploratory paired t-tests to examine initial signals of changes in psychosocial measures, and performed explanatory-sequential mixed methods to integrate data sources.

resultsWe screened 12 dyads and enrolled 7. RT-CA exceeded most feasibility and acceptability benchmarks (>70 % on 7 of 8). In exploratory analyses, participants experienced preliminary, yet meaningful reductions in emotional distress (HADS anxiety survivors: mean [95 % CI] = -5.4 [-3.4, -7.5], p < 0.001; depression survivors = -5.1 [-2.2, -8], p < 0.01; anxiety caregivers = -3.1 [-0.8, -5.5], p < 0.05; depression caregivers = -3.5 [-8, 1.1], p > 0.05). Mixed-methods analysis indicated general concordance between quantitative and qualitative data.

conclusionResults support preliminary feasibility of RT-CA. Further testing in a randomized controlled trial is now required.

trial registrationClinicaltrials.gov #NCT06517394.

Indexed as

CaregiversHeart ArrestResilience, PsychologicalSurvivorsAdaptation, PsychologicalAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedMindfulnessPsychological DistressQuality of LifeAnxietyCardiac arrest survivorshipCaregiversClinical trialsDepressionResilience

Identifiers

PMID41062056
PMCPMC13156817

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.