ReviewThe Biochemical journal2025
Cell membrane asymmetries and cellular aging.
Review in The Biochemical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Saccharomyces cerevisiae, a widely studied unicellular eukaryotic model, multiplies and divides through an asymmetric budding process, where a mother cell produces a smaller daughter cell. Although cells age across successive cell divisions, provided the mother is not too old, each daughter cell inherits a full lifespan potential. Extensive studies in budding yeast have established a framework for understanding how asymmetric cell division contributes to this lifespan resetting. One postulate of this framework is that the capacity of mother cells to bud daughters with full replicative potential is critically dependent on membraneassociated mechanisms that enable asymmetric inheritance of aging factors. Despite the identification of numerous asymmetrically distributed proteins, an integrated catalog detailing their roles in aging has not been compiled. This review provides a comprehensive resource of asymmetrically distributed membrane proteins in yeast that have a role in replicative aging. Existing knowledge governing the establishment and maintenance of asymmetry is synthesized, and gaps in our understanding of how membrane asymmetry contributes to cellular aging are identified.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.