ReviewBMJ open ophthalmology2025
OCT and OCTA quantitative metrics for polypoidal choroidal vasculopathy.
Review in BMJ open ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Predictors of response to bevacizumab monotherapy in polypoidal choroidal vasculopathy: a 12-month retrospective study.International journal of retina and vitreous · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polypoidal choroidal vasculopathy (PCV) is characterised by distinctive polypoidal lesions, recurrent serosanguineous retinal pigment detachments and branched neovascular networks. The incidence of PCV is notably higher among Asian populations, leading to inferior clinical outcomes in the absence of intervention. The relationship between PCV and neovascular age-related macular degeneration remains a controversial. The advent of optical coherence tomography (OCT) and OCT angiography (OCTA) technologies has revolutionised our approach to understanding PCV pathogenesis. Innovative OCT and OCTA biomarkers, including double layer sign, the sign of polyps, vessel density, the diameter of choroidal vessels, choroidal vascularity index, and choroidal vortex have emerged as critical imaging parameters for elucidating the pathological intricacies of PCV. Quantitative analysis of the choroid has become an essential adjunct for investigating the mechanisms underlying PCV. This comprehensive review encapsulates the array of quantitative OCT and OCTA biomarkers vital for the diagnosis, prognosis, and clinical management of this complex ocular condition.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.