Evidence map›Paper›PMID 41071000›Full record

ArticleBiomarkers in medicine2025

Triglyceride-glucose index as a novel biomarker for mild cognitive impairment in patients with coronary artery disease.

Lanxin Feng, Jianan Li, Xin Zhao, Jianqiao Song, Shuwen Yang, Xiaoyi Wang, Chenyang Liu, Min Zhang, Chenchen Tu, Xiantao Song

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lanxin FengDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China.
Jianan LiDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China.
Xin ZhaoDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China.
Jianqiao SongZhongshan School of Medicine, Sun Yat Sen University, Guangzhou, P.R. China.
Shuwen YangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China.
Xiaoyi WangDepartment of Research and Development, Beijing Wispirit Technology Co. Ltd, Beijing, P.R. China.
Chenyang LiuDepartment of Research and Development, Beijing Wispirit Technology Co. Ltd, Beijing, P.R. China.
Min ZhangDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China.
Chenchen TuDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China.
Xiantao SongDepartment of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with coronary artery disease (CAD) are at an increased risk of cognitive impairment, yet reliable noninvasive biomarkers for identifying high-risk individuals in this population remain scarce. This study aimed to investigate the association between the triglyceride-glucose (TyG) index and cognitive function in patients with CAD.

methodsThis study included 1163 patients with CAD who underwent cognitive function assessment. Multiple regression analyses were conducted to evaluate the relationship between the TyG index and cognitive function. Furthermore, receiver operating characteristic (ROC) curve analysis was conducted to determine the discriminatory ability of the TyG index in identifying patients with mild cognitive impairment (MCI).

resultsThe TyG index was negatively correlated with Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) scores (

conclusionThe TyG index is independently associated with cognitive function in patients with CAD, with elevated values associated with an increased risk of MCI.

Indexed as

Blood GlucoseCognitive DysfunctionCoronary Artery DiseaseTriglyceridesAgedBiomarkersFemaleHumansMaleMiddle AgedROC CurveBiomarkersBlood GlucoseTriglyceridescognitive functioncoronary artery diseaseinsulin resistanceMild cognitive impairmenttriglyceride-glucose index

Identifiers

PMID41071000
PMCPMC12542614

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.