Evidence map›Paper›PMID 41075788›Full record

Trial reportCell reports. Medicine2025

Food- vs. supplement-based very-low-energy diets and gut microbiome composition in women with high body mass index: A randomized controlled trial.

Melissa M Lane, Amelia J McGuinness, Mohammadreza Mohebbi, Mojtaba Lotfaliany, Amy Loughman, Martin O'Hely, Adrienne O'Neil, Jessica Batti, Mark Kotowicz, Michael Berk and 5 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cell reports. Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Melissa M LaneDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia. Electronic address: m.lane@deakin.edu.au.
Amelia J McGuinnessDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia.
Mohammadreza MohebbiDeakin University, Faculty of Health, Biostatistics Unit, Geelong, VIC, Australia.
Mojtaba LotfalianyDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia.
Amy LoughmanUniversity of Melbourne, Melbourne School of Psychological Sciences, Melbourne, VIC, Australia.
Martin O'HelyMurdoch Children's Research Institute, Parkville, VIC, Australia; Deakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine and Barwon Health, Geelong, VIC, Australia.
Adrienne O'NeilDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia.
Jessica BattiDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia.
Mark KotowiczDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia; Department of Medicine-Western Health, The University of Melbourne, St Albans, VIC, Australia; Barwon Health, University Hospital, Geelong, VIC, Australia; Deakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine and Barwon Health, Geelong, VIC, Australia.
Michael BerkDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia; Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, Florey Institute for Neuroscience and Mental Health and the Department of Psychiatry, The University of Melbourne, Melbourne, VIC, Australia; Deakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine and Barwon Health, Geelong, VIC, Australia.
Lucy SaundersDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), School of Medicine and Barwon Health, Geelong, VIC, Australia.
Richard PageBarwon Health, University Hospital, Geelong, VIC, Australia; Barwon Centre of Orthopaedic Research and Education, Deakin University, Geelong, VIC, Australia.
Sally BeattieBarwon Centre of Orthopaedic Research and Education, Deakin University, Geelong, VIC, Australia.
Wolfgang MarxDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia.
Felice N JackaDeakin University, the Institute for Mental and Physical Health and Clinical Translation (IMPACT), Food & Mood Centre, School of Medicine and Barwon Health, Geelong, VIC, Australia; Centre for Adolescent Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; College of Public Health, Medical & Veterinary Sciences, James Cook University, Townsville, QLD, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a single-blind, two-arm, randomized controlled-feeding trial (May 2021-February 2022), 47 women (30-65 years, BMI 30-45 kg/m

Indexed as

Body Mass IndexCaloric RestrictionDietary SupplementsGastrointestinal MicrobiomeAdultAgedFemaleHumansMiddle AgedSingle-Blind Methodalpha diversitybeta diversitydietary interventionfood processinggut microbiomeobesityrandomized controlled trialtaxonomic compositionvery-low-energy dietwomen

Identifiers

PMID41075788
PMCPMC12629797

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.