ReviewFrontiers in veterinary science2025
Feline immunodeficiency virus: current insights into pathogenesis, clinical impact, and advances in treatment and vaccine development.
Review in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Field evaluation of two commercial feline immunodeficiency virus antibody detection point-of-care kits in domestic cats.BMC veterinary research · 2026Article
- Comparative evaluation of nine lateral flow assays for FIV antibody detection using an in-house ELISA as a reference method.BMC veterinary research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Feline immunodeficiency virus (FIV) is a retrovirus that infects both domestic and wild cats worldwide, causing a progressive decline in the immune function. FIV infection is a major concern for cat owners, particularly those with outdoor cats or multi-cat households, as it can lead to chronic illness and a reduced lifespan. The development of effective prevention and treatment strategies for FIV is therefore essential to improve the health and welfare of cats. This review article provides an overview of current knowledge on FIV, covering its epidemiology, prevalence, pathogenesis, risk factors, transmission, and management. It also discusses the various FIV subtypes, their geographical distribution, and their associations with different clinical outcomes. In addition, the review examines the clinical and pathophysiological features associated with FIV, including oral and respiratory infections, neurological disorders, renal diseases, and cancer. The review also discusses management strategies for FIV-infected cats, with a focus on advances in the development of antiretroviral drugs and immunomodulators. This review highlights the challenges of developing an effective FIV vaccine and provides a comprehensive summary of the latest advancements in FIV vaccine research. Additionally, it offers an overview of adjuvants used so far in FIV vaccine candidates and explores the potential application of adjuvants currently licensed for other vaccines. Overall, this review paper provides a comprehensive and up-to-date summary of current knowledge on FIV, highlighting key areas that require further research to improve treatment and prevention of this important feline viral infection.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.