Evidence map›Paper›PMID 41080195›Full record

ArticleNeuro-oncology practice2025

The CARING intervention for neuro-oncology family caregivers: Randomized controlled trial feasibility, eSNAP/caregiver navigation engagement, and acceptability.

Hyojin Choi, Steven K Sutton, Deanna Witte, Nina Pastore, Kristen J Wells, Bradley J Zebrack, Peter Forsyth, Margaret M Byrne, Maija Reblin

Abstract read
In one paragraph

Article in Neuro-oncology practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hyojin ChoiDepartment of Family Medicine, University of Vermont, Burlington, Vermont, USA.
Steven K SuttonDepartment of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, Florida, USA.ORCID https://orcid.org/0000-0002-2504-7601
Deanna WitteDepartment of Health Outcomes & Behavior, Moffitt Cancer Center, Tampa, Florida, USA.
Nina PastoreDepartment of Family Medicine, University of Vermont, Burlington, Vermont, USA.
Kristen J WellsDepartment of Psychology, San Diego State University, San Diego, California, USA.ORCID https://orcid.org/0000-0002-7359-8678
Bradley J ZebrackSchool of Social Work, University of Michigan, Ann Arbor, Michigan, USA.
Peter ForsythNeuro-Oncology Program, Moffitt Cancer Center, Tampa, Florida, USA.ORCID https://orcid.org/0000-0002-3756-8594
Margaret M ByrneDepartment of Health Outcomes & Behavior, Moffitt Cancer Center, Tampa, Florida, USA.ORCID https://orcid.org/0000-0002-8143-4702
Maija ReblinDepartment of Family Medicine, University of Vermont, Burlington, Vermont, USA.ORCID https://orcid.org/0000-0003-3108-465X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To address the unmet support needs of neuro-oncology family caregivers, our team developed an 8-week intervention, CARING. CARING consists of electronic Social Network Assessment Program (eSNAP), a web-based tool to identify and organize support resources, and manualized navigation sessions for caregivers. Our objective is to evaluate the methodological feasibility of our randomized controlled trial (RCT) study design, and caregiver engagement and acceptability of CARING. Methods: The RCT compared CARING to a waitlist control. RCT feasibility was evaluated based on caregiver and patient recruitment and retention. CARING intervention engagement was evaluated via caregiver participation data over 8 weeks. CARING intervention acceptability was evaluated via quantitative satisfaction scales, as well as qualitative debrief interviews of caregiver participants at 8 weeks. Results: Of 502 potentially eligible patient-caregiver dyads approached, 148 consented (29%). Although effective, randomization was ended due to mid-study coronavirus disease (COVID)-related administrative issues that impacted recruitment rates. In the last year, all participants were assigned to the intervention condition to prioritize the evaluation of CARING. Of those enrolled, 87% of caregivers and 77% of patients completed the Week-8 assessment. Of the 81 caregivers assigned to CARING, 88% used eSNAP at least once, and 73% engaged with 6+ navigation topics. At 8 weeks, 77% of caregivers reported that they liked CARING and 81% found it helpful. Qualitative data provided additional insights into intervention acceptability. Conclusions: Results suggest that the RCT methodology used is feasible, and neuro-oncology caregivers engaged with CARING components and found the intervention acceptable. Future studies can apply key lessons in developing or implementing other caregiver interventions.

Indexed as

brain neoplasmcaregiverspatient navigationpsychosocial interventionsocial support

Identifiers

PMID41080195
PMCPMC12508752

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.