ReviewCurrent gastroenterology reports2025
Exploring Recent Advances in Colon-targeted Drug Delivery Systems: from Traditional Methods to Advanced Technologies.
Review in Current gastroenterology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Water-triggered in-situ gelling phospholipid oil enema for enhanced budesonide delivery and mucosal healing in ulcerative colitis.International journal of pharmaceutics: X · 2026Article
- Self-rolling film foriScience · 2026Article
- Microrobots for Precision Diagnosis and Treatment in the Digestive System: A Review of Actuation Mechanisms, Structural Design, Preclinical and Translational Applications.Micromachines · 2026Review
- 3D Bioprinting of an Oral Colon Delivery System for Precision Bacteriotherapy.Pharmaceutics · 2026Article
- Formulation approaches for colon-specific drug delivery: conventional to nanocarrier systems.RSC advances · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review examines various colon-targeted drug delivery systems (CTDDS) and their implications for the treatment of colonic disorders. RECENT
findingsRecent studies have demonstrated substantial advancements in CTDDS by the development of pH-dependent, enzyme-responsive, and time-controlled formulations designed for enhancing site-specific delivery and reducing systemic adverse effects. Advanced methodologies, such as ligand or receptor-mediated targeting and multifunctional systems that incorporate various triggering mechanisms, are demonstrating encouraging outcomes in improving therapeutic efficacy. Furthermore, innovative methods like pressure, osmotic-controlled systems, and 3D printing technologies are also being explored for their ability to ensure precise drug release in the colonic region. CTDDS enables localized, controlled therapy, which has the potential to enhance colonic disease outcomes. Integrating the knowledge of the colon's physiology with new delivery technologies may help future research and facilitate the development of more effective treatments.
Indexed as
Identifiers
41082057What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.