ArticlePrenatal diagnosis2025
Fetal Pancreas in Growth Restriction: A Prenatal Window Into Metabolic and Genetic Risk.
Article in Prenatal diagnosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- From double bubble sign to definitive diagnosis: prenatal ultrasound evaluation of congenital duodenal obstruction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026Article
- The Contribution of Ultrasound and Doppler Studies on Impaired Intrauterine Conditions and the Development of Future Disease.Medicina (Kaunas, Lithuania) · 2026Review
- Diameter of the fetal pancreas and abdomen-to-pancreas-ratio: novel ultrasound parameters in fetal growth restriction.Archives of gynecology and obstetrics · 2026Article
- Fetal Pancreas in Growth Restriction: A Prenatal Window Into Metabolic and Genetic Risk.Prenatal diagnosis · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAnimal models have demonstrated impaired pancreatic islet development in fetal growth restriction (FGR) cases, which can become apparent at or before birth and persist into adulthood, resulting in glucose intolerance. This study assessed the relationship between fetal pancreatic biometry and FGR.
methodsA retrospective cohort study included fetuses diagnosed with FGR who underwent prenatal ultrasound at a tertiary center. Pancreatic circumference was measured and compared with established normative reference values. Associations between pancreatic size and estimated fetal weight (EFW), abdominal circumference (AC), Doppler findings, gestational age (GA), concurrent gestational diabetes mellitus (GDM), and the presence of anatomical or genetic abnormalities were analyzed.
resultsThe study group comprised 69 cases. The mean GA at the ultrasound examination and pancreatic measurement was 31.5 ± 3.5 weeks. Pancreatic circumference was at or smaller than the 50th percentile of normative references in the majority of the cohort (75%), with 36.2% of cases falling below the 10th percentile and 27.5% below the 5th percentile. Pancreas size correlated moderately with EFW (r = 0.53) and AC (r = 0.54) but not with GA.
conclusionFetuses with FGR exhibited reduced pancreatic size. These findings highlight the pancreas as a novel imaging marker and warrant further investigation into long-term metabolic programming.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.