Evidence map›Paper›PMID 41082324›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

CDK4/6 Inhibition Induces CD8

Lin He, Yuzhong Peng, Lat-Lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh Haipeng Lei, Yongqin Ye, Yangyang Feng and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lin HeCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.ORCID https://orcid.org/0000-0002-7390-1702
Yuzhong PengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Lat-Lun LeongUniversity Hospital, Macau University of Science and Technology, Macau SAR, 999078, China.
Jingbo ZhouGuangdong Key Laboratory of New Technology in Rice Breeding, Rice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, China.
Dongyang TangCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Weilu WangMedical Sciences Division, Macau University of Science and Technology, Macau SAR, 999078, China.
Xiaoran WuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Josh Haipeng LeiCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Yongqin YeMedical Sciences Division, Macau University of Science and Technology, Macau SAR, 999078, China.
Yangyang FengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Yunfeng QiaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Xiangpeng ChuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Di MuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Qi ZhaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Tzuming LiuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.
Yan ChenMedical Sciences Division, Macau University of Science and Technology, Macau SAR, 999078, China.
Paul Kwonghang TamMedical Sciences Division, Macau University of Science and Technology, Macau SAR, 999078, China.
Chu-Xia DengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, 999078, China.ORCID https://orcid.org/0000-0001-8033-3902

Funding

Chair Professor Grant (CPG) 2025-00035-FHSMacao Science and Technology Development Fund 0009/2022/AKPMacao Science and Technology Development Fund 0054/2023/RIA1Macao Science and Technology Development Fund FDCT: 0129/2024/RIA2Natural Science Foundation of China (NSFC) 82030094University of Macau Multiyear Grant (MYRG) 2023-00029-FHSUniversity of Macau Multiyear Grant (MYRG) GRG2024-00073-FHS
6 · The paper itself

Abstract

Cyclin-dependent kinases 4 and 6 (CDK4/6) regulate cell cycle progression from the G

Indexed as

Breast NeoplasmsCD8-Positive T-LymphocytesCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6Intramolecular OxidoreductasesMacrophage Migration-Inhibitory FactorsTumor-Associated MacrophagesAnimalsCell Line, TumorFemaleHumansMiceTumor MicroenvironmentCDK6 protein, humanCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6Intramolecular OxidoreductasesMacrophage Migration-Inhibitory FactorsMif protein, mouseCD8+ T cellCDK4/6 inhibitorcell–cell communicationtumor‐associated macrophagetumor immune microenvironment

Identifiers

PMID41082324
PMCPMC13292170

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.