Evidence map›Paper›PMID 41083202›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2025

Endocrine enigmas: vascular health in females throughout the lifespan.

Jenna C Stone, Margie H Davenport, Kerrie L Moreau, Kyra E Pyke, Megan M Wenner, Jennifer S Williams, Maureen J MacDonald

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jenna C StoneDepartment of Kinesiology, McMaster University, Hamilton, Ontario, Canada.ORCID 0009-0001-5528-072X
Margie H DavenportFaculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0001-5627-5773
Kerrie L MoreauDivision of Geriatric Medicine, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0001-9298-047X
Kyra E PykeFaculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0002-1818-3867
Megan M WennerDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0003-0055-783X
Jennifer S WilliamsFaculty of Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-9501-7662
Maureen J MacDonaldDepartment of Kinesiology, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-9851-3610

Funding

Exerkines and the heterogeneity of peripheral and cerebral vascular adaptations to exercise training with aging in women and menR01AG089069 · UNIVERSITY OF COLORADO DENVER · 2025 to 2025
$1.3M
NightWare Therapeutic Platform for improving Cardiovascular Health inAdults With Nightmares Associated with PTSDR21AG075544 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2023 to 2023
$194k
Canadian Government | Canadian Institutes of Health Research (CIHR) Postdoctoral FellowshipCanadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) Canadian Graduate Scholarship (Doctoral)Canadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) Discover GrantCanadian Government | Veterans Affairs Canada (VAC) CX002762CSRD VA I01 CX002762Heart and Stroke Foundation of Canada (HSF) Heart & Stroke Doctoral Personnel AwardHHS | National Institutes of Health (NIH) R01AG089069NIA NIH HHS R01 AG089069NIA NIH HHS R21 AG075544NIA NIH HHS R56 AG072094NIA NIH HHS U54 AG062319University of Alberta (UofA) Christenson Professorship in Active Healthy Living
6 · The paper itself

Abstract

It is well established that gonadal hormones, such as estrogen and progesterone, influence vascular function and structure. Premenopausal females experience fluctuations in these hormones during each menstrual cycle, transiently during pregnancy, and during the menopause transition; yet the impact of these hormonal fluctuations on vascular health remains something of an enigma. This review aims to unravel this enigma by

Indexed as

AgingBlood VesselsCardiovascular DiseasesMenstrual CycleAge FactorsAnimalsEstrogensFemaleHumansMenopausePregnancyEstrogensarterial stiffnessendothelial functionmenopausemenstrual cyclepregnancy

Identifiers

PMID41083202
PMCPMC12581107

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.