Evidence map›Paper›PMID 41084620›Full record

ArticleTherapeutic advances in infectious disease

Microbiological characterization of bacteremia in patients with chemotherapy-induced febrile neutropenia: systematic review and meta-analysis.

Alvarez Franklin Correa, Paola Guasti, Luis Fuenmayor-González, Harold Alexander-León, Yunqi Yu Liu, Johana Elizabeth Salgado-Apunte, Jorge González Grijalva, Hernan Sánchez, Nayely García-Méndez, María Fernanda García-Aguilera

Abstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alvarez Franklin CorreaFacultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.ORCID https://orcid.org/0000-0002-7803-0029
Paola GuastiFacultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.
Luis Fuenmayor-GonzálezFacultad de Ciencias Médicas, Universidad Central del Ecuador, Quito, Ecuador.ORCID https://orcid.org/0000-0001-6141-7692
Harold Alexander-LeónHospital Oncológico SOLCA Quito, Quito, Ecuador.ORCID https://orcid.org/0000-0001-6261-636X
Yunqi Yu LiuHospital Oncológico SOLCA Quito, Quito, Ecuador.ORCID https://orcid.org/0009-0003-3148-5530
Johana Elizabeth Salgado-ApunteHospital Oncológico SOLCA Quito, Quito, Ecuador.ORCID https://orcid.org/0000-0002-0040-2451
Jorge González GrijalvaHospital Oncológico SOLCA Quito, Quito, Ecuador.ORCID https://orcid.org/0009-0007-7087-2145
Hernan SánchezHospital Oncológico SOLCA Quito, Quito, Ecuador.ORCID https://orcid.org/0009-0000-1353-3162
Nayely García-MéndezUniversidad de La Frontera, Doctorado de Ciencias Médicas, Temuco, Chile.ORCID https://orcid.org/0000-0002-2251-8148
María Fernanda García-AguileraUniversidad de La Frontera, Doctorado de Ciencias Médicas, Temuco, Chile.ORCID https://orcid.org/0000-0002-5375-3474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Febrile neutropenia (FN) is the most common and serious adverse event of chemotherapy for solid and hematological neoplasms, with infection as a major complication. FN occurs in 10%-50% of patients with solid tumors and over 80% with hematological malignancies, with mortality rates up to 11%. Objective: To characterize bloodstream pathogens in post-chemotherapy FN through a systematic review and meta-analysis of studies published from 2013 to February 13, 2024. Design: Systematic review and meta-analysis. Data sources and methods: PubMed, Web of Science, Scopus, and Embase were searched using MeSH, Emtree, and keywords. Risk of bias was assessed using the JBI checklist. Random-effects proportions meta-analysis was performed. Results: Twenty-two studies ( Conclusion: Gram-negative pathogens slightly predominate over Gram-positives in bloodstream infections among post-chemotherapy FN patients. Trial registration: PROSPERO (CRD42023472191).

Indexed as

bacteremiaepidemiologyfebrile neutropenia induced by chemotherapyfungemiasepsis

Identifiers

PMID41084620
PMCPMC12515338

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.