Evidence map›Paper›PMID 41084997›Full record

ArticleJournal of clinical ultrasound : JCU

Application of Multimodal Ultrasound Combined With BI-RADS in Classification and Diagnosis of Non-Mass Breast Lesions.

Zengdi Yang, Yongyan Lyu, Yanting Yang, Cuiping Xu, Keke Zhang, Xuxu Yang, Feng Chen, Lanlan Cheng, Minglei Ren

Abstract read
In one paragraph

Article in Journal of clinical ultrasound : JCU. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Non-Mass Breast Lesions or General Malignancy Features?Journal of clinical ultrasound : JCU · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zengdi YangDepartment of Medical Ultrasound, The 901st Hospital of the Joint Logistics Support Force, Hefei City, China.
Yongyan LyuDepartment of Medical Ultrasound, The 901st Hospital of the Joint Logistics Support Force, Hefei City, China.
Yanting YangHefei Customs Port Outpatient Department, Anhui International Travel Healthcare Center, Hefei City, China.
Cuiping XuDepartment of Medical Ultrasound, The 901st Hospital of the Joint Logistics Support Force, Hefei City, China.
Keke ZhangDepartment of Medical Ultrasound, The 901st Hospital of the Joint Logistics Support Force, Hefei City, China.
Xuxu YangDepartment of Medical Ultrasound, The 901st Hospital of the Joint Logistics Support Force, Hefei City, China.
Feng ChenDepartment of Medical Ultrasound, The 901st Hospital of the Joint Logistics Support Force, Hefei City, China.
Lanlan ChengPathology Department, The 901st Hospital of the Joint Logistics Support Force, Hefei City, China.
Minglei RenDepartment of Medical Ultrasound, The 901st Hospital of the Joint Logistics Support Force, Hefei City, China.ORCID https://orcid.org/0009-0004-7400-3746

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe primary objective of this study is to assess the diagnostic accuracy of multimodal ultrasound, including microvascular flow imaging (MVFI), shear wave elastography (SWE), and contrast-enhanced ultrasound (CEUS), in conjunction with the breast imaging reporting and data system (BI-RADS) for non-mass breast lesions (NMLs).

methodsA total of 100 patients who received treatment in our hospital from April 2021 to June 2024 were retrospectively collected. All patients had complete pre-operative ultrasound BI-RADS, MVFI, SWE, and CEUS. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated; the diagnostic efficacy of the methods was compared, and the diagnostic performance of the subjects was plotted.

resultsThe agreement between the BI-RADS-MVFI-SWE-CEUS alone and the pathological results was very high, with a Kappa value of 0.806. The area under the curve (AUC) of the combined diagnosis of MVFI-SWE-CEUS and BI-RADS-MVFI-SWE-CEUS was 0.885 (p < 0.001) and 0.922 (p < 0.001). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of BI-RADS-MVFI-SWE-CEUS for the diagnosis of NMLs were higher than those of the diagnosis alone (p < 0.05), with 95.24%, 89.19%, 93.75%, 91.67%, and 93%, respectively.

conclusionThe combination of multimodal ultrasound and BI-RADS provides a significant improvement in the diagnostic accuracy and sensitivity for NMLs, offering a more comprehensive and reliable diagnostic tool for evaluating NMLs.

Indexed as

Breast NeoplasmsMultimodal ImagingUltrasonography, MammaryAdultAgedBreastContrast MediaElasticity Imaging TechniquesFemaleHumansMiddle AgedPredictive Value of TestsReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityContrast MediaBI‐RADScontrast‐enhanced ultrasoundmultimodal ultrasoundnon‐mass breast lesionsshear wave elastographysuperb microvascular imaging

Identifiers

PMID41084997
PMCPMC12967728

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.