Evidence map›Paper›PMID 41085959›Full record

ArticleEJNMMI radiopharmacy and chemistry2025

Quantitative dual-isotope preclinical SPECT/CT imaging and biodistribution of the mercury-197m/g theranostic pair with [

Parmissa Randhawa, Cristina Rodríguez-Rodríguez, Helena Koniar, Patrick R W J Davey, Shaohuang Chen, Valery Radchenko, Caterina F Ramogida

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Parmissa RandhawaDepartment of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada.ORCID http://orcid.org/0000-0002-7280-5524
Cristina Rodríguez-RodríguezFaculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada.ORCID http://orcid.org/0000-0002-3313-4422
Helena KoniarLife Sciences, TRIUMF, 4004 Wesbrook Mall, Vancouver, BC, V6T 2A3, Canada.ORCID http://orcid.org/0000-0003-0794-9115
Patrick R W J DaveyDepartment of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada.ORCID http://orcid.org/0000-0002-8774-0030
Shaohuang ChenDepartment of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada.ORCID http://orcid.org/0000-0002-0112-7949
Valery RadchenkoLife Sciences, TRIUMF, 4004 Wesbrook Mall, Vancouver, BC, V6T 2A3, Canada.ORCID http://orcid.org/0000-0002-4742-6565
Caterina F RamogidaDepartment of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada. cfr@sfu.ca.ORCID http://orcid.org/0000-0003-4815-2647

Funding

CIHR GR021373Natural Sciences and Engineering Research Council of Canada 07207-2019Natural Sciences and Engineering Research Council of Canada RGPIN-2018-04997New Frontiers in Research Fund - Transformation NFRFT-2022-00269
6 · The paper itself

Abstract

backgroundMercury-197m (

resultsRadiolabeling of H

conclusionsThese results establish Tetrathiol as a promising scaffold for mercury-based theranostics, offering efficient radiolabeling and in vivo stability. The integration of high-resolution imaging and HgQuant-based quantification of each isomer establishes a comprehensive framework for advancing [

Indexed as

ChelatorsHg2+Mercury-197Phantom imagingSPECTTetrathiolTheranostics

Identifiers

PMID41085959
PMCPMC12521730

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.